Biosurfactants produced by Serratia species: Classification, biosynthesis, production and application

Clements, Tanya; Ndlovu, Thando; Khan, S. Ajmal; Khan, Wesaal

doi:10.1007/s00253-018-9520-5

Cited by 60 publications

(36 citation statements)

References 67 publications

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“…Compound 1 showed a molecular ion peak [M+H] + at m/z 670.4401 (calculated for 670.4386, ∆m = +2.2 ppm) in the ESI-HRMS spectrum, consistent with the molecular formula of C 33 H 59 N 5 O 9 . Analysis of 1D and 2D NMR spectra of compound 1 indicated the presence of five amino acids: threonine, valine, isoleucine and two serine residues and the presence of long alkyl chain, leading to its identification as a stephensiolide I analogue upon comparison with existing literature (Figure 3) [19,20]. The MS/MS spectrum of compound 1 confirmed the previous annotated structure through the detection of immonium ions and the classical peptide sequencing.…”

Section: Isolation and Identification Of Molecules From Lecanicilliumsupporting

confidence: 69%

“…The proposed structures of the isolated molecules can be used to propagate the annotation to other connected MS/MS spectra. By comparison with literature data, the non-isolated molecules could be identified as stephensiolides A, B and E [19,20] ( Figure 2B). The absolute configuration of these identified and isolated compounds could not be confirmed.…”

Section: Isolation and Identification Of Molecules From Lecanicilliummentioning

confidence: 81%

“…Hence, it is for the first time that these compounds are isolated from a fungus. They had been described so far only once, from a bacterium associated with mosquitoes' metabolites from the Serretia genus [19,20]. This is the reason for the absence of these uncommon compounds in the available MS/MS databases.…”

Section: Discussionmentioning

confidence: 99%

“…The isolated compounds were identified as stephensiolides I (1), D (2), G (3), C (4) and stephensiolide F (5) by comparison with spectroscopic data from available literature ( Figure 3) [19,20]. The proposed structures of the isolated molecules can be used to propagate the annotation to other connected MS/MS spectra.…”

Section: Isolation and Identification Of Molecules From Lecanicilliummentioning

confidence: 99%

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Identification of Antimicrobial Compounds from Sandwithia guyanensis-Associated Endophyte Using Molecular Network Approach

Mai

Levasseur

Buisson

et al. 2019

Plants

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The emergence of multidrug resistant bacterial pathogens and the increase of antimicrobial resistance constitutes a major health challenge, leading to intense research efforts being focused on the discovery of novel antimicrobial compounds. In this study, endophytes were isolated from different parts of Sandwithia guyanensis plant (leaves, wood and latex) belonging to the Euphorbiaceae family and known to produce antimicrobial compounds, and chemically characterised using Molecular Network in order to discover novel antimicrobial molecules. One fungal endophyte extract obtained from S. guyanensis latex showed significant antimicrobial activity with Minimal Inhibitory Concentration on methicillin-resistant Staphylococcus aureus at 16 µg/mL. The chemical investigation of this fungus (Lecanicillium genus) extract led to the isolation of 5 stephensiolides compounds, four of which demonstrated antibacterial activity. Stephensiolide I and G showed the highest antibacterial activity on MRSA with a MIC at 4 and 16 µg/mL respectively.Plants 2020, 9, 47 2 of 11 chemical constituents of a wide variety of extracts in a single map [5,6]. Furthermore, MN offers the possibility to map additional information, such as biological, analytical and taxonomical details over networks [6][7][8]. In this study, we applied a related multi-informative prioritisation strategy based on the use of MN, with the aim of finding new antimicrobial structures from of a set of extracts from 42 Euphorbiaceae endophytes.The Euphorbiaceae family comprises approximately 283 genera and 7300 species, and has been found in various morphological types, including herbs, shrubs and trees [9]. Some species of the family are used as lubricants and purgatives, while others are used as a source of medicinal drugs for the treatment of diarrhoea, inflammation and swelling. Their milky latex secretions impart several toxic effects such as dermatitis, severe irritation to the eyes and stomach discomfort. Moreover, Euphorbia sp. latex has been shown to possess moderate antimicrobial properties and ability to protect against herbivores [10]. Together, the antimicrobial, insecticidal and toxicity properties of Euphorbia latex makes it a hostile environment for microbes and plant-feeding insect pests. However, it has been recently highlighted that Euphorbia sp. latex contains unexpectedly complex bacterial and fungal communities [11]. Meanwhile, endophytes, which are microorganisms residing in plant tissues without inducing any diseases in the host plants, have been shown to defend themselves as well the plants from pathogens and have a crucial role in plant survival. They also improve the ecological adaptability of the hosts by enhancing their tolerance to environmental stresses and resistance to phytopathogens and/or herbivores [12]. In addition, endophytes residing within plants may produce identical or similar secondary metabolites as their host plant, and therefore, have also been recognised as a potential source of novel bioactive molecules. These common compounds ...

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Section: Isolation and Identification Of Molecules From Lecanicilliumsupporting

confidence: 69%

Section: Isolation and Identification Of Molecules From Lecanicilliummentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Isolation and Identification Of Molecules From Lecanicilliummentioning

confidence: 99%

See 2 more Smart Citations

Identification of Antimicrobial Compounds from Sandwithia guyanensis-Associated Endophyte Using Molecular Network Approach

Mai

Levasseur

Buisson

et al. 2019

Plants

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show abstract

“…Rhamnolipids are molecules isolated from certain microbes using fermentation, that is, Pseudomonas aeruginosa, Burkholderia sp., Pseudomonas sp. (Clements, Ndlovu, Khan, & Khan, 2018). They consist of glycolipids composed of hydrophilic rhamnose groups and a hydrophobic hydrocarbon chain.…”

Section: Rhamnolipidsmentioning

confidence: 99%

Nanoemulsions: Using emulsifiers from natural sources replacing synthetic ones—A review

Dammak

Sobral

Aquino

et al. 2020

Comp Rev Food Sci Food Safe

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In recent years, substantial consideration within the food industry has been aimed at the development of food‐grade nanoemulsions (NE) as promising systems for encapsulating, stabilizing, and delivering bioactive compounds. Although numerous studies have revealed the critical potential of NE, there are still several challenges to overcome them. These include the extensive amounts of synthetic emulsifiers needed for NE formulation, which can potentially be toxic for human health. The interest in safety, and natural emulsifiers have stimulated food manufacturers to develop "label‐friendly" formulations by replacing synthetic emulsifiers with natural alternatives. This review represents a critical and comprehensive summary of the application of natural emulsifiers as potential substitutes for synthetic emulsifiers in NE production, with particular emphasis on the newly identified natural emulsifiers. Some recent reports showed the excellent emulsifying properties of various natural emulsifier extracted from natural resources, to produce NE, and therefore, might be generalized for further industrial applications. Future trends are encouraged to identify novel natural emulsifiers from industrial food by‐products that may demonstrate highly effective emulsifiers.

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Application of Microorganisms in Biosurfactant Production

Pedraza-Segura

Rodríguez‐Durán

Saucedo‐Castañeda

et al. 2021

Bioprospecting of Microorganism‐Based Industrial Molecules

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Biosurfactants produced by Serratia species: Classification, biosynthesis, production and application

Cited by 60 publications

References 67 publications

Identification of Antimicrobial Compounds from Sandwithia guyanensis-Associated Endophyte Using Molecular Network Approach

Identification of Antimicrobial Compounds from Sandwithia guyanensis-Associated Endophyte Using Molecular Network Approach

Nanoemulsions: Using emulsifiers from natural sources replacing synthetic ones—A review

Application of Microorganisms in Biosurfactant Production

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