Biosorption, bioaccumulation and food chain transfer of organic chemicals : report prepared by F. A. P. C. Gobas and D. Mackay

Abstract

The final three chapters of the report present a series of calculation procedures for bioconcentrat ion and biomagni f icat ion and laboratory methods for the investigation of bioconcentration phenomena. A comprehensive bibliography of approximately 120 references, as well as an appendix of selected relevant physicochemical properties for priority chemicals and bioconcentration data are also reported. The information provided in this report establishes a good data base, to assist the Ontario Ministry of the Environment in setting effluent limits based on receiving water quality. These effluent limits will, in turn, be compared with technology based effluent limits, derived through the MISA process. Such comparisons will greatly enhance the Ontario Ministry of the Environment's ability to recommend/evaluate load reductions achieved through the MISA program. And, as well, provide guidance and rationale for future policy decisions. Research and monitoring activities on the Great Lakes will, based on the information in this report, endeavour to incorporate design strategies, which more efficiently and reliably obtains data critical to those models addressing Food Chain Bioaccumulat ion dynamics

Differential Scanning Calorimetry Study of the Interaction of Antidepressant Drugs, Noradrenaline, and 5-Hydroxytryptamine with a Membrane Model

“…new. Various authors have demonstrated the existence of mathematical relationships between the buffer-membrane and buffer-octanol partition coefficients in a very quantitative way.23.24 Gabas et al 23 were able to show that for molecules having a molar volume of <300 cm3/mol, as is the case here (Table III), the correlation between the two coefficients was regular and increasing. It seems essential to add that simply considering the partition coefficient POlw does not make it possible to determine the interactions and localization of the drug within a membrane-like organization.…”

Bioconcentration of Polycyclic Aromatic Compounds from Sediments to Muscle of Finfish

“…Integrating gives /f =fJDJ{Dw + Dm)]{l -exp[-(Dw + Dm)t/VFZF}} (5) The concentration in the fish is then CF or ZF/F at any time. This uptake equation is commonly expressed in rate constant form as (39): (6) It can be shown that k\ is Dw/ VFZW, k2 is Dw/VfZf, and km is Dm/VFZp (18).…”

A Review on Detection and Abatement of Heavy Metals

“…The model is a non‐steady‐state mass balance model for hydrophobic organic chemicals based on a Lake Ontario food chain. The food chain bioaccumulation model was proposed and enhanced by Gobas as well as Arnot and Gobas (2004) , . The models assumption is that the change in concentration of a chemical in an organism with time is a result of the rate of uptake and loss of the chemical.…”