Biosensors on Enzymes, Tissues, and Cells

Guo, Xiaoxi; Kuhlmann, Julia; Heineman, William R.

doi:10.1007/978-1-4939-0676-5_11

Cited by 5 publications

(2 citation statements)

References 176 publications

(73 reference statements)

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“…Regarding transducing elements, chemical sensors and biosensors can be categorized into electrochemical (potentiometric, amperometric, and conductometric) sensors, optical (including reflectometry or absorptiometry, fluorescence, and surface plasmon resonance [SPR]) and surfaceenhanced Raman spectroscopy (SERS) assay sensors, piezoelectric sensors, and thermal sensors, which can convert reactions or binding with target species into a digital signal (Scheme 1B) [13,15,[17][18][19].…”

Section: Scheme 1 22 Sensing Techniques For Food Quality and Safetymentioning

confidence: 99%

Progress in sensory devices of pesticides, pathogens, coronavirus, and chemical additives and hazards in food assessment: Food safety concerns

Shenashen

Emran

Sabagh

et al. 2022

Progress in Materials Science

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Section: Scheme 1 22 Sensing Techniques For Food Quality and Safetymentioning

confidence: 99%

Progress in sensory devices of pesticides, pathogens, coronavirus, and chemical additives and hazards in food assessment: Food safety concerns

Shenashen

Emran

Sabagh

et al. 2022

Progress in Materials Science

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“…The large number of oxidase enzymes enabled this concept to be expanded for the detection of numerous other substrates. 73 For example, a biosensor based on lactate oxidase is used for determination of lactate in blood, which is useful for establishing intensive training regimens such as in swimming, marathon running and horse racing Electrochemical affinity assays/biosensors.-The concept of combining selective "capture" of an analyte by a biological binding agent with electrochemical detection was another major step forward. The idea stems from radioimmunoassay (RIA), which was invented and developed into a powerful technique by Solomon Berson and Rosalyn Yalow, with Yalow receiving the 1977 Nobel Prize.…”

Section: Liquid Chromatography With Electrochemical Detection (Lcec)-mentioning

confidence: 99%

Editors’ Choice—Review—From Polarography to Electrochemical Biosensors: The 100-Year Quest for Selectivity and Sensitivity

Heineman

Kissinger

Wehmeyer

2021

J. Electrochem. Soc.

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This is a story of the 100-year path for voltammetric electroanalytical chemistry from the serendipitous discovery of polarography by Jaroslav Heyrovsky in 1922 to the miniature biosensors of today. In spite of issues with the dropping mercury electrode (DME), polarography was dominant for almost 50 years due to the good quantitative results it produced. Then, significant developments led to today’s methods with drastic improvements in detectable concentration and amount, selectivity, ease of use, and breadth of application. Important steps forward include the shift from the DME to solid electrodes, the strategic modification of electrode surfaces chemically and with membranes, electrochemistry in thin layers of solution with the associated decrease in sample amount from milliliters to microliters and below, liquid chromatography with electrochemical detection, more powerful and smaller instrumentation, microfabrication of electrodes, pulse techniques that improved concentration limits of detection by discriminating against double layer charging, spectroelectrochemistry for enhanced selectivity by electrochemically changing a spectroscopic signal, cyclic voltammetry for the general utility that makes it the work-horse of voltammetry, and biosensors that dramatically expanded the applicability of voltammetry through the use of nature’s biological catalysts (enzymes) and capture agents (antibodies, aptamers).

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