Biosensors for Point Mutation Detection

Jiang, Hanlin; Xi, Hui; Juhas, Mario; Zhang, Yang

doi:10.3389/fbioe.2021.797831

Cited by 2 publications

(1 citation statement)

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“…Moreover, electrochemical sensors can be used for genetic disease screening, such as detecting mutations or variations in specific genes associated with inherited disorders. By incorporating DNA probes or aptamers specific to the target genetic sequence, electrochemical sensors can identify genetic mutations and variations linked to diseases like cystic fibrosis, sickle cell anemia, and genetic predisposition to certain cancers [87][88]. Again more, electrochemical sensors have applications in the diagnosis and monitoring of neurological disorders.…”

Section: Disease Diagnosismentioning

confidence: 99%

Carbon nanomaterial-based electrochemical sensor in biomedical application, a comprehensive study

Majumdar,

Shahazi,

Saddam

et al. 2024

Charact. Appl. Nanomater.

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Recently, carbon nanocomposites have garnered a lot of curiosity because of their distinctive characteristics and extensive variety of possible possibilities. Among all of these applications, a development of sensors with electrochemical properties based on carbon nanocomposites for use in biomedicine has shown as an area with potential. These sensors are suitable for an assortment of biomedical applications, such as prescribing medications, disease diagnostics, and biomarker detection. They have many benefits, including outstanding sensitivity, selectivity, and low limitations on detection. This comprehensive review aims to provide an in-depth analysis of the recent advancements in carbon nanocomposites-based electrochemical sensors for biomedical applications. The different types of carbon nanomaterials used in sensor fabrication, their synthesis methods, and the functionalization techniques employed to enhance their sensing properties have discussed. Furthermore, we enumerate the numerous biological and biomedical uses of electrochemical sensors based on carbon nanocomposites, among them their employment in illness diagnosis, physiological parameter monitoring, and biomolecule detection. The challenges and prospects of these sensors in biomedical applications are also discussed. Overall, this review highlights the tremendous potential of carbon nanomaterial-based electrochemical sensors in revolutionizing biomedical research and clinical diagnostics.

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Section: Disease Diagnosismentioning

confidence: 99%