Biosensors: Enzyme Sensors

Takeda, Kouta; Nakamura, Nobuhumi

doi:10.1016/b978-0-12-822548-6.00042-x

Cited by 3 publications

(4 citation statements)

References 152 publications

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“…-Enzyme sensors [40]; -Immunosensors, which use antibodies, antibody fragments, antigens, or antigen conjugates as biorecognition elements [41]; -Aptasensors (DNA-based biosensors), which use nucleic acid molecules as biorecognition elements [42];…”

Section: 0mentioning

confidence: 99%

Biosensors for Food Mycotoxin Determination: A Comparative and Critical Review

Pisoschi,

Iordache,

Stanca

et al. 2024

Chemosensors

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The need for performant analytical methodologies to assess mycotoxins is vital, given the negative health impact of these compounds. Biosensors are analytical devices that consist of a biological element for recognizing the analyte and a transducer, which translates the biorecognition event into a signal proportional to the analyte concentration. The biorecognition elements can be enzymes, antibodies, or DNA fragments. The modalities of detection can be optical, electrochemical, thermal, or mass-sensitive. These analytical tools represent viable alternatives to laborious, expensive traditional methods and are characterized by specificity given by the biorecognition element, sensitivity, fast response, portability, multi-modal detection, and the possibility of in situ application. The present paper focuses on a comprehensive view, enriched with a critical, comparative perspective on mycotoxin assay using biosensors. The use of different biorecognition elements and detection modes are discussed comparatively. Nanomaterials with optical and electrochemical features can be exploited in association with a variety of biorecognition elements. Analytical parameters are reviewed along with a broad range of applications.

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Section: 0mentioning

confidence: 99%

Biosensors for Food Mycotoxin Determination: A Comparative and Critical Review

Pisoschi,

Iordache,

Stanca

et al. 2024

Chemosensors

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“…The operating principle relies on direct electron transfer (DET) between the enzyme and the electrode, avoiding the use of various media. [46,51] Therefore, this type of biosensors is also known as a DET-type biosensors, which could avoid nonspecific manipulation between the used media and contaminants compared to second-generation biosensors. [52] However, the electroactive center of the enzyme is generally inside the protein, and electrons cannot be transferred between the electroactive center and the electrode as quickly as possible.…”

Section: Enzyme-based Electrochemical Biosensorsmentioning

confidence: 99%

“…[44] The enzyme-based biosensor consists of two modules, the enzyme plays the role of recognition elements and bioreceptor, and the transducer is able to generate optical or electrical signals. [45] According to the working principle of the enzyme-based biosensor (Figure 3), [46] the enzyme is able to specifically recognize when a target analyte is present in the system, undergoing a change in color, substance, mass, light absorption or emission. These changes can cause a change in the electrical or optical signal of the biosensor.…”

Section: Enzyme-based Electrochemical Biosensorsmentioning

confidence: 99%

“…The third‐generation enzyme‐based biosensors are very simple structure consisting of only two parts, the enzyme and the electrode. The operating principle relies on direct electron transfer (DET) between the enzyme and the electrode, avoiding the use of various media [46,51] . Therefore, this type of biosensors is also known as a DET‐type biosensors, which could avoid non‐specific manipulation between the used media and contaminants compared to second‐generation biosensors [52] .…”

Section: Electrochemical Biosensors From Mxenes‐based Nanomaterialsmentioning

confidence: 99%

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Rapid Advances of Versatile MXenes for Electrochemical Enzyme‐Based Biosensors, Immunosensors, and Nucleic Acid‐Based Biosensors

Yao

Fan³

et al. 2022

ChemElectroChem

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Electrochemical biosensors have played an important role in clinical diagnostics, drug analysis, environmental monitoring, food safety, and other fields. Versatile two-dimensional (2D) MXenes-based nanomaterials, born with intrinsic peculiarities including high electrical conductivity, low toxicity, large specific surface area, and good biocompatibility, provide sufficient potential candidates for the construction of universal or specific electrochemical biosensors. In this review, we summarized the latest advances in 2D MXenes nanomaterials for constructing electrochemical enzyme-based biosensors, immunosensors, and nucleic acid-based biosensors in 2021, and then discussed the pertinent roles of corresponding 2D MXenes and carried out a comparison of the difference in the detection limit and detection range. Finally, challenges and future prospects of 2D MXenes-based electrochemical biosensors are proposed and discussed.

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5．インスリン受容体の標的認識部位を利用したインスリンモニタリングシステムの開発

FUNABASHI

2024

Denki Kagaku

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Biosensors: Enzyme Sensors

Cited by 3 publications

References 152 publications

Biosensors for Food Mycotoxin Determination: A Comparative and Critical Review

Biosensors for Food Mycotoxin Determination: A Comparative and Critical Review

Rapid Advances of Versatile MXenes for Electrochemical Enzyme‐Based Biosensors, Immunosensors, and Nucleic Acid‐Based Biosensors

5．インスリン受容体の標的認識部位を利用したインスリンモニタリングシステムの開発

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