Biosensitivity of Molybdenum Disulfide for Monitoring Breast Cancer Marker CA15-3 Using Quartz Crystal Microbalance

Lin, Suhua

doi:10.20964/2021.01.02

Cited by 5 publications

(2 citation statements)

References 25 publications

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“…The use of the second antibody could also amplify the mass change on the QCM chip surface. Lin et al [ 105 ] used a sandwich detection strategy to realize the detection and signal amplification of CA15-3. First, a two-dimensional nanomaterial MoS 2 film was coated on the surface of the QCM chip, and the first antibody of CA15-3 was modified on the MoS 2 film by physical adsorption.…”

Section: Biosensormentioning

confidence: 99%

A Review of Biosensors for Detecting Tumor Markers in Breast Cancer

Hong

Sun

et al. 2022

Life

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Breast cancer has the highest cancer incidence rate in women. Early screening of breast cancer can effectively improve the treatment effect of patients. However, the main diagnostic techniques available for the detection of breast cancer require the corresponding equipment, professional practitioners, and expert analysis, and the detection cost is high. Tumor markers are a kind of active substance that can indicate the existence and growth of the tumor. The detection of tumor markers can effectively assist the diagnosis and treatment of breast cancer. The conventional detection methods of tumor markers have some shortcomings, such as insufficient sensitivity, expensive equipment, and complicated operations. Compared with these methods, biosensors have the advantages of high sensitivity, simple operation, low equipment cost, and can quantitatively detect all kinds of tumor markers. This review summarizes the biosensors (2013–2021) for the detection of breast cancer biomarkers. Firstly, the various reported tumor markers of breast cancer are introduced. Then, the development of biosensors designed for the sensitive, stable, and selective recognition of breast cancer biomarkers was systematically discussed, with special attention to the main clinical biomarkers, such as human epidermal growth factor receptor-2 (HER2) and estrogen receptor (ER). Finally, the opportunities and challenges of developing efficient biosensors in breast cancer diagnosis and treatment are discussed.

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Section: Biosensormentioning

confidence: 99%

A Review of Biosensors for Detecting Tumor Markers in Breast Cancer

Hong

Sun

et al. 2022

Life

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“…In [112], authors applied QCM sensors to detect the biomarker CA15-3 associated with breast cancer and observed the following: (a) the one-dimensional ZnO nanostructure was appropriate for biosensor application; (b) the QCM sensor showed good stability with a response time of 10 s; (c) QCM had high sensitivity (25.34 ± 0.67 Hz/scale (1 U/mL)); (d) a linear (0.99) pattern associated with CA15.3 was observed for a range of 0.5 to 26 U/mL. In [113], the authors considered QCM for monitoring breast cancer marker CA15-3 and found that QCM sensors had high sensitivity (26. 303 ± 1.139 Hz/scale, 1 U/mL) and good linearity (0.960 ± 0.013) in the 0.5 U/mL and 100 U/mL concentration range of CA15-3.…”

Section: Quartz Crystal Microbalance Biosensormentioning

confidence: 97%

Exploring the Potential of Sensing for Breast Cancer Detection

Chowdhury,

Wang,

et al. 2023

Applied Sciences

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Breast cancer is a generalized global problem. Biomarkers are the active substances that have been considered as the signature of the existence and evolution of cancer. Early screening of different biomarkers associated with breast cancer can help doctors to design a treatment plan. However, each screening technique for breast cancer has some limitations. In most cases, a single technique can detect a single biomarker at a specific time. In this study, we address different types of biomarkers associated with breast cancer. This review article presents a detailed picture of different techniques and each technique’s associated mechanism, sensitivity, limit of detection, and linear range for breast cancer detection at early stages. The limitations of existing approaches require researchers to modify and develop new methods to identify cancer biomarkers at early stages.

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Direct glucose fuel cell towards a self-powered point-of-care nanobiosensor

Sá¹

2023

Fundamentals of Sensor Technology

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Biosensitivity of Molybdenum Disulfide for Monitoring Breast Cancer Marker CA15-3 Using Quartz Crystal Microbalance

Cited by 5 publications

References 25 publications

A Review of Biosensors for Detecting Tumor Markers in Breast Cancer

A Review of Biosensors for Detecting Tumor Markers in Breast Cancer

Exploring the Potential of Sensing for Breast Cancer Detection

Direct glucose fuel cell towards a self-powered point-of-care nanobiosensor

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