Biosensing with cell phones

Preechaburana, Pakorn; Suska, Anke; Filippini, Daniel

doi:10.1016/j.tibtech.2014.03.007

Cited by 85 publications

(51 citation statements)

References 32 publications

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“…Finally, the migration of integrated versions of biosensor platforms to current cell phones, with their advanced imaging and communication capabilities, represents a powerful approach for the achievement of affordable LOCbased biosensors [43]. The high-performance cameras [44,45], processing power, data acquisition, and constantly upgraded software of existing smartphones make them an attractive complement for the development of multiplexed biosensor devices.…”

Section: Breakthroughs In Multiplexing and Loc Platformsmentioning

confidence: 99%

Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration

et al. 2016

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Abstract:Motivated by the recent progress in the nanofabrication field and the increasing demand for cost-effective, portable, and easy-to-use point-of-care platforms, localized surface plasmon resonance (LSPR) biosensors have been subjected to a great scientific interest in the last few years. The progress observed in the research of this nanoplasmonic technology is remarkable not only from a nanostructure fabrication point of view but also in the complete development and integration of operative devices and their application. The potential benefits that LSPR biosensors can offer, such as sensor miniaturization, multiplexing opportunities, and enhanced performances, have quickly positioned them as an interesting candidate in the design of lab-on-a-chip (LOC) optical biosensor platforms. This review covers specifically the most significant achievements that occurred in recent years towards the integration of this technology in compact devices, with views of obtaining LOC devices. We also discuss the most relevant examples of the use of the nanoplasmonic biosensors for real bioanalytical and clinical applications from assay development and validation to the identification of the implications, requirements, and challenges to be surpassed to achieve fully operative devices.

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Section: Breakthroughs In Multiplexing and Loc Platformsmentioning

confidence: 99%

Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration

et al. 2016

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“…In contrast with this instrumentation approach, other solutions aim at partially or totally retaining cell phone ubiquity by excluding electronic interfacing and employing either reusable accessories (Breslauer et al, 2009;Smith et al, 2011;Zhu et al, 2013;Vashist et al, 2014;Mudanyali et al, 2012;Switz et al, 2014;Potyrailo, 2013; http://holomic.com) or disposable devices (Matinez et al, 2008a;Preechaburana et al, 2012aPreechaburana et al, , 2014Preechaburana et al, , 2015Comina et al, 2015a) to complement cell phones for biosensing and chemical detection. These techniques dominantly exploit optical coupling to cell phone cameras, which represents a universally available resource across phone models, brands and operating systems.…”

Section: Introductionmentioning

confidence: 99%

“…The chemical element in these systems should thus produce responses readable as images or video. The main approaches include microscopy and detection of intensity and color changes, as well as contrast and displacement signals and their time responses (Vashist et al, 2014;Preechaburana et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

“…Further demands include autonomy in operating the entire sample conditioning process and the creation of a reference calibration range to allow quantitative measurements while operating the phone in default configurations and integrating the coupling element within the disposable (Preechaburana 2012a(Preechaburana , 2014Comina et al, 2015a). This concept presents specific challenges in terms of integration and design, and this review will examine the lab-on-a-chip (LOC) biosensing that could be adapted to such end-to-end universal, autonomous and quantitative diagnostic disposables for cell phones analyses.…”

Section: Introductionmentioning

confidence: 99%

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Towards autonomous lab-on-a-chip devices for cell phone biosensing

Comina

Suska

Filippini

2016

Biosensors and Bioelectronics

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Modern cell phones are a ubiquitous resource with a residual capacity to accommodate chemical sensing and biosensing capabilities. From the different approaches explored to capitalize on such resource, the use of autonomous disposable lab-on-a-chip (LOC) devices conceived as only accessories to complement cell phones underscores the possibility to entirely retain cell phones ubiquity for distributed biosensing. The technology and principles exploited for autonomous LOC devices are here selected and reviewed focusing on their potential to serve cell phone readout configurations. Together with this requirement, the central aspects of cell phones resources that determine their potential for analytical detection are examined. The conversion of these LOC concepts into universal architectures that are readable on unaccessorized phones is discussed within this context. (C) 2015 Elsevier B.V. All rights reserved.

Funding Agencies|Swedish Research Council (VR) [C0453801]; Carl Tryggers Foundation [CTS14140]

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“…It is anticipated that SPSs will find wide applications in personal healthcare, environment monitoring, food safety, and homeland security. 5,6 For example, a smartphone accessible blood glucose meter was recently launched by iHealth Lab Inc. This meter is just slightly larger than a quarter.…”

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confidence: 99%

Smartphone-Based Sensors

Gao

2016

Electrochem. Soc. Interface

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Smartphones are finding increasing applications in sensors. Smartphones can be used as the sensing signal reader and the sensing transducer, or to enable sensors via a wireless network. In addition, sensors can be combined with the global positioning system (GPS) in the smartphone to allow positioning of sensing and mapping of target analytes. Therefore, portable smartphone-based sensor (SPS) systems have great potential for field-deployable or point-of-care applications. This article presents recent progress in the SPS system development.

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Biosensing with cell phones

Cited by 85 publications

References 32 publications

Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration

Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration

Towards autonomous lab-on-a-chip devices for cell phone biosensing

Smartphone-Based Sensors

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