Biosensing applications of titanium dioxide coated graphene modified disposable electrodes

Kuralay, Filiz; Tunç, Selma; Bozduman, Ferhat; Öksüz, Lütfi; Öksüz, Ayşegül Uygun

doi:10.1016/j.talanta.2016.07.037

Cited by 33 publications

(9 citation statements)

References 25 publications

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“…In the last decades, numerous studies have been conducted involving auto-organized nanostructures of different metal oxides and semiconductors, which have received considerable attention due to the potential technological uses of these materials [11,12]. In this way, in order to increase the versatility of the physicochemical properties for different applications, novel modification strategies of nanostructured TiO 2 films have been investigated [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Comparative study of the anchorage and the catalytic properties of nanoporous TiO2 films modified with ruthenium (II) and rhenium (I) carbonyl complexes

Oyarzún

Chardon‐Noblat

Pérez

et al. 2018

Chemical Physics Letters

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In this article we study the anchoring of cis-[Ru(bpyC 4 pyr)(CO) 2 (CH 3 CN) 2 ] 2+ , cis-[Ru(bpy) 2 (CO) 2 ] 2+ and cis-[Ru(bpyac)(CO) 2 Cl 2 ], onto nanoporous TiO 2 employing electropolymerization, electrostatic interaction and chemical bonding. Also, the [Re(bpyac)(CO) 3 Cl] rhenium(I) complex for chemical anchorage was analyzed. The characterization of TiO 2 /Ru(II) and TiO 2 /Re(I) nanocomposite films was performed by field emission scanning electron microscopy (FESEM), electron dispersive X-ray spectroscopy (EDS) and Raman spectroscopy. In addition, for the more stable nanocomposites obtained, the catalytic properties (solar energy conversion and CO 2 reduction) were evaluated. The efficiency improvement in redox process derived from the (photo)electrochemical evidence indicates that modified nanoporous TiO 2 structures enhance the rate of charge transfer reactions.

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Section: Introductionmentioning

confidence: 99%

Comparative study of the anchorage and the catalytic properties of nanoporous TiO2 films modified with ruthenium (II) and rhenium (I) carbonyl complexes

Oyarzún

Chardon‐Noblat

Pérez

et al. 2018

Chemical Physics Letters

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“…This thiol diluent not only helps DNAp robes to stand up,b ut also prevents unspecific adsorptionso fo ther species on the surface because of the high surface coverage. However, recent studies indicatet hat binarym onolayers based on DNAa nd MCH still display unspecificb ackground contributions due to incomplete backfillinga nd to the existence of surface defects that may lead to erroneous signalsa nd low reproducibility [10].I no rder to solve these problems some authors propose the use of ternary monolayers [11][12][13][14][15].…”

Section: T His Results Hasmentioning

confidence: 99%

Key Factors of Ternary Monolayers to Improve DNA Sensors Performance

et al. 2016

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An important factor affecting the performance of electrochemical genosensors is the immobilization strategy used to anchor the capture probes (CP) on the electrode surface. One of the most common immobilization systems involves the formation of self‐assembled monolayers of thiolated probes on gold surfaces, mainly due to its simplicity and effectiveness. Recent studies have shown that in two‐component thiolated DNA and mercaptohexanol (MCH) monolayers, there is incomplete backfilling that leads to defective surface blockage, producing unspecific background signal. In order to solve these problems, ternary monolayers have been proposed, in which besides MCH as primary diluent, a second diluent is added to enhance the hybridization efficiency and anti‐fouling properties of the surface. Herein, we report a thorough evaluation of different surface chemistries using two different sensors, one for the detection of a peanut allergen encoding sequence and the other one targeting a gluten‐encoding sequence. We assessed the relationship between CP length and the chemical characteristics of the diluents. Factors such as concentration, nature of the functional groups and chain length of the second diluent were evaluated. We found that length of diluents affects primarily the hybridization efficiency, while the type of functional groups, e.g. hydroxyl, carboxyl or a second thiol group, influences the degree of surface coverage. Results diverged between the two sensors evaluated.

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“…Au [30][31][32] and TiO 2 [24,33,34] have been widely applied as transducers in biosensors. This is due to their high stability, biocompatibility, high surface-to-volume ratio, and strong amplification effect on signals.…”

Section: Role Of Tio 2 Nanomaterials In Biosensormentioning

confidence: 99%

State-of-the-Art on Functional Titanium Dioxide-Integrated Nano-Hybrids in Electrical Biosensors

Nadzirah

Gopinath

Parmin

et al. 2020

Critical Reviews in Analytical Chemistry

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Biosensors operating based on electrical methods are being accelerated toward rapid and efficient detection that improve the performance of the device. Continuous study in nano-and material-sciences has led to the inflection with properties of nanomaterials that fit the trend parallel to the biosensor evolution. Advancements in technology that focuses on nano-hybrid are being used to develop biosensors with better detection strategies. In this sense, titanium dioxide (TiO 2) nanomaterials have attracted extensive interest in the construction of electrical biosensors. The formation of TiO 2 nano-hybrid as an electrical transducing material has revealed good results with high performance. The modification of the sensing portion with a combination (nano-hybrid form) of nanomaterials has produced excellent sensors in terms of stability, reproducibility, and enhanced sensitivity. This review highlights recent research advancements with functional TiO 2 nano-hybrid materials, and their victorious story in the construction of electrical biosensors are discussed. Future research directions with commercialization of these devices and their extensive utilizations are also discussed.

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Biosensing applications of titanium dioxide coated graphene modified disposable electrodes

Cited by 33 publications

References 25 publications

Comparative study of the anchorage and the catalytic properties of nanoporous TiO2 films modified with ruthenium (II) and rhenium (I) carbonyl complexes

Comparative study of the anchorage and the catalytic properties of nanoporous TiO2 films modified with ruthenium (II) and rhenium (I) carbonyl complexes

Key Factors of Ternary Monolayers to Improve DNA Sensors Performance

State-of-the-Art on Functional Titanium Dioxide-Integrated Nano-Hybrids in Electrical Biosensors

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