Bioremediation of alpechin

Ramos‐Cormenzana, A.; Monteoliva‐Sánchez, Mercedes; López, M.J.

doi:10.1016/0964-8305(95)00033-2

Cited by 94 publications

(38 citation statements)

References 18 publications

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“…Olive oil waste effluents are major pollulants in the Mediterranean area and represent a severe environmental problem because of its content of large amounts of phenolic compounds, which have antimicrobial and phytotoxic activities (9,10,15,22). Ramos-Cormenzana et al (27) suggested that olive mill wastewater could be used as an alternative, low-cost substrate for EPS production because of its high carbon/nitrogen ratio, which is similar to that of standard media used for polysaccharide production. In the study described here, an EPS with interesting BRM properties was purified from culture supernatants of strain CP-7 grown in an olive oil wastewater-based medium.…”

Section: Discussionmentioning

confidence: 99%

Biological Response Modifier Activity of an Exopolysaccharide fromPaenibacillus jamilaeCP-7

Ruiz‐Bravo

Jiménez-Valera

Moreno

et al. 2001

Clin Diagn Lab Immunol

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An extracellular polysaccharide was purified from culture supernatants of Paenibacillus jamilae CP-7, a gram-positive bacillus that was isolated from compost prepared with olive mill wastewaters. The extracellular polysaccharide was produced under aerobic conditions in a medium containing olive mill wastewaters (80% [vol/vol]). This exopolymer had a low level of acute toxicity when it is administered to BALB/c mice by the intraperitoneal route. Interesting immunomodulatory effects were detected when mice were given 10 mg of exopolysaccharide per kg of body weight; the proliferative responses of splenocytes to B-cell and T-cell mitogens were suppressed, the in vitro levels of production of gamma interferon and granulocyte-macrophage colony-stimulating factor by unstimulated and lipopolysaccharide-stimulated splenocytes were enhanced, and the levels of resistance to the intracellular pathogen Listeria monocytogenes was increased in mice. Also, the exopolysaccharide was able to induce lymphocyte proliferation in vitro. We conclude that P. jamilae produces an exopolysaccharide with interesting immunomodulatory properties.Microbial exopolysaccharides (EPSs) often show clearly identified properties that form the basis for a wide range of applications in food, pharmaceutical, petroleum, and other industries (32). Thus, several EPSs have been shown to possess immunological activities with potential pharmacological applications as biological response modifiers (BRMs). BRMs are agents that alter the normal immune response and whose mechanisms of action include induction of cytokines (29). Research on pharmacological applications of BRMs has led to development of both immunosuppressive and immunostimulating drugs that are effective in preventing the rejection of transplanted organs, for the treatment of some autoimmune diseases, as cancer immunotherapy, or as adjuvants for vaccine construction (14). Lentinan and other fungal glucans, yeast mannan fractions, and a number of bacterial EPSs have been identified as BRMs and have been found to have the ability to stimulate tumor rejection (for a review, see reference 40). In recent years, research has focused on the mechanisms of action of these compounds (12, 41), as well as on the discovery of new ones (7,33).Although polysaccharides are considered to be T-cell-independent antigens, a number of microbial EPSs are immunomodulators, with activities for T cells and macrophages (for a review, see reference 35). Polysaccharide A, a component of the capsular complex of Bacteroides fragilis, possesses mitogenic activity for T lymphocytes (6), and the production of interleukin-2 (IL-2) by CD4ϩ T cells appears to play an essential role in the in vivo immunomodulation by this EPS (37). A number of fungi and yeasts produce ␤-(1,3)-glucans with immunomodulatory properties (4, 35). Studies on the mechanisms of immunomodulation by a soluble derivative of ␤-(1,3)-glucan have shown that it has the ability to prime granulocytes and macrophages for enhanced cytokine release (30), reactive nitr...

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Section: Discussionmentioning

confidence: 99%

Biological Response Modifier Activity of an Exopolysaccharide fromPaenibacillus jamilaeCP-7

Ruiz‐Bravo

Jiménez-Valera

Moreno

et al. 2001

Clin Diagn Lab Immunol

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“…Indeed, OMW can be a source of water especially in the arid zones of southern Morocco. In addition, OMW contains large amounts of minerals and organic matter that can be beneficial to plant growth (Ramos-Cormenzana et al 1995). Nevertheless, because of its phytotoxic and antimicrobial effects related mainly to the presence of phenolic compounds, organic volatile acids, acidic pH and the high level of salts such as potassium (Paredes et al 1999), raw OMW can not be used without prior treatment.…”

Section: Introductionmentioning

confidence: 99%

Detoxification of olive mill wastewaters by Moroccan yeast isolates

Sassi¹,

Ouazzani

Walker

et al. 2007

Biodegradation

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A total of 105 yeast strains were isolated from Moroccan olive oil production plants and evaluated for their ability to grow in olive oil mill wastewaters (OMW). The 9 isolates that grew best on OMW were selected for further study to evaluate their effect on removal of organic pollutants and OMW phytotoxicity (barley seed germination test). The results showed that at least four yeast isolates effectively lowered the toxicity of this effluent in addition to providing very useful materials in terms of both yeast biomass (6 g/l DW) and an irrigation fluid. This group of yeast isolates significantly reduced the concentration of total phenols (44% removal) and Chemical Oxygen Demand, COD (63% removal). The best germination rate of 80% for undiluted OMW was obtained for strain Candida holstii that also increased the pH from 4.76 to 6.75. Principal component analysis of the results obtained for the best yeast strains confirmed the importance of COD and total phenol reduction along with increase of organic nitrogen and final pH for the improvement of germination rates and phytotoxic reduction. This study has highlighted the potential of indigenous yeasts in detoxification of olive mill wastewaters.

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“…López and Ramos-Cormenzana (1996) showed the possibility of obtaining 4.4 g L -1 of Xanthan with 3POMWW diluted to 30%-40%. The 3POMWW have also been studied as a source of natural pigments (anthocyanins) and different exopolysaccharides, and as a growth medium for algae (Ramos-Cormenzana et al, 1995). 3POMWW have been used as a growth media for the microbial production of extra-cellular lipase (D'Annibale et al, 2006) and for composting with olive leaves (Michailides et al, 2011).…”

Section: Three-phase Olive Mill Wastewater (3pomww)mentioning

confidence: 99%