Bioreceptor-free, sensitive and rapid electrochemical detection of patulin fungal toxin, using a reduced graphene oxide@SnO2 nanocomposite

Graphene-Based Field-Effect Transistor for Ultrasensitive Immunosensing of SARS-CoV-2 Spike S1 Antigen

“…This effect has already been reported in FETs, which can be attributed to the change in doping level due to the interaction of Ag–Ab at the reactive site on graphene and the solution interface that essentially changes the overall electrostatic potential (Δ q ) of the channel, which causes the Dirac point to shift (Δ V Dirac = Δ q / C ), where C is the gate capacitance of Gr-FET. 18 , 44 It is important to note that the large surface area of graphene leads to more efficient sensing by providing a greater number of active sites for Ag–Ab interaction. For quantitative analysis of device response, the sensitivity of the device was evaluated by calculating the change in channel resistance (Δ R ) (in %) by selecting R PB as the baseline.…”

Carbon-Based Nanocomposite Smart Sensors for the Rapid Detection of Mycotoxins

“…For example, a rGO/SnO 2 composite for the electrochemical detection of PAT that does not require a biological or chemical receptor or specific antibodies was synthesized, which showed outstanding performance and demonstrated promising electrochemical properties in the direct detection of PAT levels in contaminated apple juice samples. The DPV response of the rGO/SnO 2 composite electrode via the changes in electrical signals generated by the reduction of PAT by SnO 2 showed a linear relationship with the PAT concentration in the 50-600 nM range and had a lower detection limit of 0.6635 nM [128]. In another study, an amperometric sensor based on a step-by-step modification of the bare GCE by graphene-multiwalled carbon nanotube-chitosan-ionic liquid (Gr-MWCNTs-Ch-IL)/collagen-IL (CG-IL)/NiO NPs for the ultrasensitive determination of OTA in juice samples was fabricated.…”

Immuno-chromatic probe based lateral flow assay for point-of-care detection of Japanese encephalitis virus NS1 protein biomarker in clinical samples using a smartphone-based approach

“…12,13 While there have been reports of highly sensitive sensors [14][15][16][17] developed for JEV antigen (Ag) detection, most of them are electrochemical-based and expensive as well as difficult to fabricate, require skilled handling, and most importantly, are not portable point-of-care (PoC) devices. [18][19][20][21][22][23][24] To overcome these limitations of existing sensors, Ag targeting immunochromatographic lateral ow assays (LFAs) are being developed for rapid bedside detection of various infectious diseases. 25,26 LFAs comprise prefabricated strips of a carrier probe containing dry reagents that are activated by addition of a uid sample, 27 and the absence/presence of the target analyte is indicated by the appearance of coloured lines on the membrane.…”