Bioreactors andin situproduct recovery techniques for acetone–butanol–ethanol fermentation

Abstract

The microbial fermentation process is one of the sustainable and environment-friendly ways to produce 1-butanol and other bio-based chemicals. The success of the fermentation process greatly relies on the choice of bioreactors and the separation methods. In this review, the history and the performance of bioreactors for the acetone-butanol-ethanol (ABE) fermentation is discussed. The subject is then focused on in situ product recovery (ISPR) techniques, particularly for the integrated extraction-gas stripping. The usefulness of this promising hybrid ISPR device is acknowledged by its incorporation with batch, fed-batch and continuous processes to improve the performance of ABE fermentation.

H‐B‐E (hexanol‐butanol‐ethanol) fermentation for the production of higher alcohols from syngas/waste gas

“…However, a potential drawback is that it can result in foam formation, above all when working with small bubbles, which can negatively affect the stability and performance of the fermentation process. Low selectivity is another potential drawback to be taken into account . Pervaporation is a membrane‐separation process.…”

“…Some studies calculated the energy needed for 1‐butanol recovery with these different techniques. For adsorption a value of 1.3 MJ kg −1 ‐butanol was reported, but it may go up to 33; using pervaporation, energy requirements between 2 and 145 MJ kg −1 ‐butanol were reported; values between 7 and 14 kg/butanol are typical for liquid–liquid extraction and finally values in the range of 14–31 MJ kg −1 butanol were reported for gas stripping …”

“…Low selectivity is another potential drawback to be taken into account. 105 Pervaporation is a membrane-separation process. It has a relatively low energy consumption and does not damage the cells.…”

Industrial production of acetone and butanol by fermentation—100 years later

“…Intelligent bioreactor design can increase productivity from the downstream side of the process by influencing the microbe (Li et al . 2016 ).…”

Evaluación energética y económica de la recuperación in situ de butanol aplicando vacío cíclico en un reactor con múltiples alimentaciones

“…Existen diferentes alternativas de recuperación in situ, tales como la extracción líquido-líquido (Grisales-Diaz y Olivar, 2017), la pervaporación (Borisov y Volkov, 2015), el gas de arrastre (Li et al, 2016), la perstracción (Heerema et al, 2011), la adsorción (Goerlitz et al, 2018), entre otras (Outram et al, 2016). De las unidades usadas en la recuperación de producto in situ (ISPR), la evaporación a vacío es una de las más interesantes por su relativo bajo costo y simplicidad (Mariano et al, 2010).…”