“…There have been few studies of the effect of thyroid deficiency on the bone in adult patients, but hypothyroidism has been reported to cause osteoporosis (Fourman, 1955) and osteomalacia (Pahlke, Schmitt-Rhode & Bartelheimer, 1960), although from the published accounts the evidence on which these claims are based is not strong. Bordier, Miravet, Matrajt, Hioco & Ryckewaert (1967) have shown that bone formation and bone résorption are reduced in hypothyroidism, but that the calcification of osteoid tissue is normal.…”