Biopsy of Small Bowel of Thai People. With Special Reference to Recovery from Asiatic Cholera and to an Intestinal Malabsorption Syndrome

Celiac and Celiac-Like Mucosal Changes of the Small Intestine

“…Baker et al [11] found fingerlike villi only in Indian fetuses while in apparently healthy adult controls 56% presented predom inantly leaf-shaped villi and 44% ridges or folds. Similar findings have been reported in Thai people [74]. In this article the term celiac-like changes refers to mucosal abnormalities similar to those seen in idiopathic sprue and celiac disease occurring in gastro intestinal disorders unrelated to the prim ary m alabsorption syndrome.…”

Histologic observations in normal and pathologic jejunaI biopsy specimens

“…Similar, but generally less severe gut lesions in comparison with the above-m entioned have been observed also in Crohn's disease: Shiner [1961], as well as in some infectious diseases such as Asiatic cholera (Sprinz [1962], Gangarosa et al [1960], Sprinz et al [1962 a]), com mon enteritis (K ing and J oske [I960]), and even during intestinal infestations by worms such as in hookworm disease (Sheehy and F loch [1964]), and after antibiotic therapy.…”

“…It has been observed (Gangarosa et al [ 1960], Sprinz et al [1962 . ]), th a t the mucosa of the sm all intestine of the native Thai people, although apparently healthy, had much shorter and stum py villi, and a more dense infiltration in the tunica propria in comparison with the mucosa of the American people.…”

Isolation of Vibrio cholerae in Homogenized Tissues of Liver, Gall Bladder and Bile in Rabbit Model

“…Formerly cholera was thought to cause sloughing of the intestinal mucosa by an inflammatory process. However, the intestinal mucosa was known to remain intact and without inflammatory changes [11]. The previous findings of mucosal sloughing were shown to be artifacts, based on autolytic postmortem changes.…”