Biopsy of Diffuse Pulmonary Lesions

Klassen, Karl P.

doi:10.1001/archsurg.1949.01240040702028

Cited by 92 publications

(9 citation statements)

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“…The overall mortality in this series was 3.0% (13 pa tients) and this correlates well with the experience of other investigators [1,23]. One patient died as a result of deve loping adult respiratory distress syndrome following the open lung biopsy.…”

Section: Discussionsupporting

confidence: 88%

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Open Lung Biopsy: A Safe, Reliable and Accurate Method for Diagnosis in Diffuse Lung Disease

Shah

Tsang²,

Goldstraw³

1992

Respiration

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The ideal method for obtaining lung tissue for diagnosis should provide high diagnostic yield with low morbidity and mortality. We reviewed all 432 patients (mean age 55 years) who underwent an open lung biopsy at this hospital over a 10-year period. Twenty-four patients (5.5%) were immunocompromised. One hundred and twenty-five patients were on steroid therapy at the time of operation. Open lung biopsy provided a firm diagnosis in 410 cases overall (94.9%) and in 20 out of 24 patients in the immunocompromised group (83.3%). The commonest diagnosis was cryptogenic fibrosing alveolitis (173 patients). Twenty-two patients (5.1%) suffered complications following the procedure: wound infection 11 patients, pneumothorax 9 patients and haemothorax 1 patient. Thirteen patients (3.0%) died following open lung biopsy, but in only 1 patient was the death attributable to the procedure itself. We conclude that open lung biopsy is an accurate and safe method for establishing a diagnosis in diffuse lung disease with a high yield and minimal risk.

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Section: Discussionsupporting

confidence: 88%

“…These include percutaneous needle aspiration [5], cutting needle biopsy [6], trephine biopsy [7], transbronchial biopsy [8][9][10] and open lung biopsy [1,11,12]. Each method varies in the degree of invasiveness, diagnostic accuracy and complication rate.…”

Section: Discussionmentioning

confidence: 99%

Open Lung Biopsy: A Safe, Reliable and Accurate Method for Diagnosis in Diffuse Lung Disease

Shah

Tsang²,

Goldstraw³

1992

Respiration

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“…Open lung biopsy was performed using a modified version of the technique first described by KLASSEN et al [15]. The most common approach used was a limited anterolateral thoracotomy via a 4±10 cm submammary incision, which allowed access to segments of all three lobes of the right lung.…”

Section: Video-assisted Thoracoscopic Lung Biopsymentioning

confidence: 99%

The effect of lung biopsy on lung function in diffuse lung disease

et al. 2000

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The aim of this study was to investigate the effect on lung function of lung biopsy used in the diagnosis of diffuse lung disease carried out by an open procedure or by video‐assisted thoracoscopy. One hundred and sixteen patients with diffuse lung disease who attended the Royal Brompton Hospital were studied retrospectively. Thirty five patients underwent open lung biopsy, and 33 video‐assisted thoracoscopic biopsy and 48 had their diagnosis made without biopsy. All patients underwent lung function tests before and after surgery, or at an interval of 3–6 months in those who did not undergo biopsy. No significant differences were found in changes in lung function between those who had and had not undergone biopsy, and the proportions of patients whose lung function improved or deteriorated were similar. Lung biopsy by an open procedure or by video‐assisted thoracoscopy did not differ in its effects on lung function. The results for older patients, those with severe disease and those with fibrosing alveolitis were the same as for the whole group. Open lung biopsy for the diagnosis of diffuse lung disease does not deleteriously affect lung function whether carried out by an open or a minimally invasive procedure.

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“…However, taking multiple biopsies have been suggested in the first published reports and in current guidelines. [3,4,22] In 2013, Blackhall et al [6] reported that a median of two biopsies significantly increases the probability of reaching a definitive diagnosis. On the other hand, sampling from either a single biopsy or multiple biopsies have not made a significant difference in providing a diagnosis in other reports.…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, we believe that patients should be approached from a multidisciplinary perspective in this regard. Klassen et al [22] 270 --Taking multiple biopsy is suggested…”

Section: Discussionmentioning

confidence: 99%

Surgical lung biopsy for differential diagnosis of interstitial lung disease

Sevim¹

2016

Turk Gogus Kalp Dama

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So nuç: Cerrahi akciğer biyopsileri, düşük olasılıkla da olsa, morbidite ve mortalite ile ilişkilidir. Tüm işlemlerde spesifik tanıya ulaşılamamaktadır. Cerrahi biyopsinin yeri, tipi ve sayısı tanı oranını anlamlı olarak etkilememektedir.Anah tar söz cük ler: İdyopatik interstisyel pnömoni; idyopatik pulmoner fibrozis; nonspesifik interstisyel pnömoni. ABSTRACTBackground: This study aims to investigate the diagnostic yield of surgical lung biopsy for the differential diagnosis of interstitial lung disease and the factors affecting diagnosis.

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Biopsy of Diffuse Pulmonary Lesions

Cited by 92 publications

References 0 publications

Open Lung Biopsy: A Safe, Reliable and Accurate Method for Diagnosis in Diffuse Lung Disease

Open Lung Biopsy: A Safe, Reliable and Accurate Method for Diagnosis in Diffuse Lung Disease

The effect of lung biopsy on lung function in diffuse lung disease

Surgical lung biopsy for differential diagnosis of interstitial lung disease

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