Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates

Skardal, Aleksander; Zhang, Jianxing; Prestwich, Glenn D.

doi:10.1016/j.biomaterials.2010.04.045

Cited by 413 publications

(346 citation statements)

References 54 publications

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“…Copyright 2017, Springer International Publishing AG.) and (C) by stacking hydrogel macrofilaments to form a cellularized tubular structure(reproduced with permission from [132]. Copyright 2010, Elsevier Ltd).…”

Section: Vascular Applicationmentioning

confidence: 99%

“…Different four-armed polyethylene glycol(PEG) derivatives called TetraPEG8 and TetraPEG13 were converted to tetra-acrylate derivatives (TetraPAcs) and these were co-crosslinked with hyaluronan acid and gelatin hydrogels into synthetic extracellular matrices (sECMs) by Skardal et al (Figure 11C) [132] . The crosslinked hydrogel composites showed improved rheological properties which are more suitable for bioprinting when compared with sECM hydrogels crosslinked with PEGDA.…”

Section: Vascular Applicationmentioning

confidence: 99%

See 1 more Smart Citation

3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering

Jang¹,

Jung²,

Pan³

et al. 2024

IJB

188

117

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Three-dimensional (3D) printing of hydrogels is now an attractive area of research due to its capability to fabricate intricate, complex and highly customizable scaffold structures that can support cell adhesion and promote cell infiltration for tissue engineering. However, pure hydrogels alone lack the necessary mechanical stability and are too easily degraded to be used as printing ink. To overcome this problem, significant progress has been made in the 3D printing of hydrogel composites with improved mechanical performance and biofunctionality. Herein, we provide a brief overview of existing hydrogel composite 3D printing techniques including laser based-3D printing, nozzle based-3D printing, and inkjet printer based-3D printing systems. Based on the type of additives, we will discuss four main hydrogel composite systems in this review: polymer-or hydrogel-hydrogel composites, particle-reinforced hydrogel composites, fiber-reinforced hydrogel composites, and anisotropic filler-reinforced hydrogel composites. Additionally, several emerging potential applications of hydrogel composites in the field of tissue engineering and their accompanying challenges are discussed in parallel.

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Section: Vascular Applicationmentioning

confidence: 99%

Section: Vascular Applicationmentioning

confidence: 99%

3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering

Jang¹,

Jung²,

Pan³

et al. 2024

IJB

188

117

View full text Add to dashboard Cite

show abstract

“…The dispensing system can extrude hydrogel from the nozzles, producing defined structures. The automated robotic system for extrusion printing is generally powered by either a pneumatic [62][63][64][65][66][67][68][69][70] or a mechanical pump [71,72] . These pumps act by applying a positive pressure on the hydrogel causing it to flow out of the nozzle.…”

Section: Materials Extrusionmentioning

confidence: 99%

Bioprinting in cardiovascular tissue engineering: a review

Lee¹,

Sing²,

Tan³

et al. 2016

IJB

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Fabrication techniques for cardiac tissue engineering have been evolving around scaffold-based and scaffold-free approaches. Conventional fabrication approaches lack control over scalability and homogeneous cell distribution. Bioprinting provides a technological platform for controlled deposition of biomaterials, cells, and biological factors in an organized fashion. Bioprinting is capable of alternating heterogeneous cell printing, printing anatomical relevant structure and microchannels resembling vasculature network. These are essential features of an engineered cardiac tissue. Bioprinting can potentially build engineered cardiac construct that resembles native tissue across macro to nanoscale.

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“…Bioprinting combine the deposition of biomaterials with cells into spatial orientations and complexities that physiologically emulate the organ geometries. This has been already initiated to bioprint vessel-like constructs using hyaluronan hydrogels crosslinked with polyethylene glycol tetracrylates (Skardal, Zhang et al 2010). The overarching goal of this application of rapid prototyping in creating scaffolds for cellular growth and tissue engineering would be to generate a whole functional and living organ adapted to the individual patient anatomy and needs.…”

Section: Other Applications and Perspectives Of Rapid Prototyping In mentioning

confidence: 99%

Rapid Prototyping for Training Purposes in Cardiovascular Surgery

Abdel-Sayed¹,

Segesser²

2011

Advanced Applications of Rapid Prototyping Technology in Modern Engineering

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Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates

Cited by 413 publications

References 54 publications

3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering

3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering

Bioprinting in cardiovascular tissue engineering: a review

Rapid Prototyping for Training Purposes in Cardiovascular Surgery

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