Biopolymer Composites With High Dielectric Performance: Interface Engineering

Deshmukh, Kalim; Ahamed, M. Basheer; Deshmukh, Rajendra R.; Pasha, S. K. Khadheer; Bhagat, Pundlik Rambhau; Chidambaram, K.

doi:10.1016/b978-0-12-809261-3.00003-6

Cited by 199 publications

(126 citation statements)

References 262 publications

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“…The ZP values found for all formulations were positive being in a range between 18.15 ± 11.2 and 38.95 ± 5.99. The positive charges found are due to free amino groups (-NH2) of chitosan that become protonated (-NH3 +) (pH 5.5) overcoming the negative groups present in HPMC (-OH) [42,43]. This hypothesis is consistent for the formulations PN12, PN13, PN14, and PN15, since it was observed that in these formulations obtained with the same proportion of CS/HPMC, a considerable increase in particle size, which may have been due to charge cancellation and absence of PN formation.…”

Section: Dynamic Light Scattering Zeta Potential and Experimental Dmentioning

confidence: 99%

Polymeric Nanoparticle Associated with Ceftriaxone and Extract of Schinopsis Brasiliensis Engler against Multiresistant Enterobacteria

et al. 2020

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Bacterial resistance has become an important public health problem. Bacteria have been acquiring mechanisms to resist the action of antimicrobial active pharmaceutical ingredients (API). Based on this, a promising alternative is the use of nanotechnology, since when the systems are presented in nanometric size, there is an increase in the interaction and concentration of the action at the target site improving the activity. Thus, this study aims to develop a polymeric nanoparticle (PN) composed of chitosan and hydroxypropylmethylcellulose, as an innovative strategy for the administration of an association between ceftriaxone and extract of S. brasiliensis, for the treatment of Enterobacteriaceae. From a Box–Behnken design, nanoparticles were obtained and evaluated using the DLS technique, obtaining the particle size between 440 and 1660 nm, IPD from 0.42 to 0.92, and positive charges. Morphological characteristics of PN by SEM revealed spherical morphology and sizes similar to DLS. Infrared spectroscopy showed no chemical interaction between the components of the formulation. The broth microdilution technique evaluated their antimicrobial activity, and a considerable improvement in the activity of the extract and the API compared to the free compounds was found, reaching an improvement of 133 times in the minimum inhibitory activity CRO.

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Section: Dynamic Light Scattering Zeta Potential and Experimental Dmentioning

confidence: 99%

Polymeric Nanoparticle Associated with Ceftriaxone and Extract of Schinopsis Brasiliensis Engler against Multiresistant Enterobacteria

et al. 2020

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“…The amino acids in the gelatine structure are mainly glycine, proline, and hydroxyproline. This unique combination and arrangement is responsible for the helicoidal shape of the chain and for the gelling properties of gelatine [13,14]. Gelatine is the most commonly used thickening/gelling agent in many industries such as in food, cosmetics, and pharmaceuticals and in the medical field.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the physicochemical properties of antimicrobial compositions with zinc oxide nanoparticles

Pulit-Prociak

Chwastowski

Rodrigues

et al. 2019

Science and Technology of Advanced Materials

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In this study, an antimicrobial composition based on polyvinyl alcohol (PVA) and zinc oxide (ZnO) was developed. The aim of the work was to obtain a film-forming product for antimicrobial treatment of surfaces. To improve the physical, mechanical, and film-forming properties of the compositions, three natural stabilizing agents were added to the formulation: gelatine, guar gum and hydroxyethyl cellulose. Formulations with different concentrations of each stabilizer were tested, and the physicochemical properties of the obtained products were measured. The size of zinc oxide particles in obtained compositions varied from 232 to 692 nm. The compositions had a slight acidic nature. Their pH ranged from 6.84 to 6.99. The average density of products was equal to 1.37 × 10 3 (kg/m 3 ). It was confirmed that zinc oxide nanoparticles do not penetrate through a model dermal membrane which is a desired effect concerning their toxicity. The antimicrobial activity of the obtained compositions was assessed against Aspergillus niger strain. After 24 h of studying, the growth inhibition was in 71% greater than in reference material. After statistical analysis of the results, it was concluded in order to achieve the most desirable physicochemical and utilitarian properties, the concentrations of gelatine, guar gum and hydroxyethylcellulose should be equal to 0.5%, 0.03% and 0.055%, respectively. ARTICLE HISTORY

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“…These two types of gelatins are commercially produced at a low cost, which makes it ideal for application in the biomedical industry for manufacturing surgical materials and capsules. The food processing industry also uses gelatin to produce gels and edible films [56].…”

Section: Collagen and Gelatinmentioning

confidence: 99%