Biopolímero produzido a partir da cana-de-áçucar para cicatrização cutânea

Abstract

Um polissacarídeo extracelular foi produzido por via microbiológica, através da bactéria ZSP isolada no Laboratório de Microbiologia Industrial da Estação Experimental de Cana-de-Açúcar do Carpina/UFRPE, apresentando excepcional capacidade de processo. Os principais monossacarídeos presentes na fração solúvel foram glicose (87,6%), xilose (8,6%), manose (0,8%), ribose (1,7%), galactose (0,1%), arabinose (0,4%) e o ácido glucurônico (0,8%). Devido ao alto índice de traumatismos que acomete os animais domésticos e a busca por alternativas simples, econômicas e capazes de proporcionar condições ideais para cicatrização, foram realizados os testes com o biopolímero produzido a partir da cana-de-açúcar em animais portadores de feridas cutâneas, a fim de avaliar a reepitelização. Observou-se o aumento do tecido de granulação, controle da infecção e diminuição do tempo de cicatrização, permitindo concluir que o biopolímero contribui para o processo cicatricial, podendo ser utilizado em feridas cutâneas.

Characterization of the deposition of collagen fibers and Lithogenic potential in bladder of rats submitted to a sugar cane biopolymer graft

“…38 (4): 544-551, July - August, 2012 of biomaterials it was developed a very compatible and pure polymer obtained from sugar cane, through a reducer process treatment of residual sugars, made only of polymered sugars and glicuronic acid: the sugar cane biopolymer (BPCA). BPCA presents elasticity, resistance to traction and flexibility that are suitable for biological grafts (4), and it has been widely used in several tissues and in many forms in animal experiments: arterial prosthesis, reconstruction of timpanic membrane, ureteral reconstruction, slings and cell conductor in cell cultures (4)(5)(6)(7)(8). In veterinary medicine, it has a very important role in biological dressings for cutaneous wounds, showing a bacteriostatic and bactericidal effect that favor healing (5).…”

“…BPCA presents elasticity, resistance to traction and flexibility that are suitable for biological grafts (4), and it has been widely used in several tissues and in many forms in animal experiments: arterial prosthesis, reconstruction of timpanic membrane, ureteral reconstruction, slings and cell conductor in cell cultures (4)(5)(6)(7)(8). In veterinary medicine, it has a very important role in biological dressings for cutaneous wounds, showing a bacteriostatic and bactericidal effect that favor healing (5). Our goal was to evaluate the integration of sugar cane biopolymer graft in rat bladders, comparing the results with those of polyglactin 910, studying the presence of bladder stones related to the behavior of the material and weight of the bladders, determining the tissue inflammatory response and bladder fibrosis of host and control rats after BPCA graft.…”

Spongy film of cellulosic polysaccharide as a dressing for aphthous stomatitis treatment in rabbits

“…The RAS is permanently exposed to mechanical trauma, as by mastication of food, also as by brushing the teeth in the case of humans. Coelho 17 related that the polysaccharide of the sugar cane forms a stable film which, when in contact with wound fluids, releases an amount of sugar which can raise the osmolarity and reduce the number of bacterial, a positive factor in the healing process.…”

“…Coelho 17 noted that the biopolymer sugar cane forms a stable film which, when in contact with wound fluids, releases an amount of sugar that can lead to concentrate and medium hyperosmolarity, which is considered irritant and a positive factor in the healing process by stimulating granulation. One concern was to study the material, how long remain fixed at the injury site and exert its biological function in ulcer site as a curative.…”

Antibacterial properties and healing effects of Melipona scutellaris honey in MRSA-infected wounds of rats

“…Several alternative therapies have been tested, among which the topical use of substances with high osmolarity 4 , with sugar and its derivatives cited as healing and antimicrobial agents 5,6 .…”