Biophotonic Strategies of Measurement and Stimulation of the Cranial and the Extracranial Lymphatic Drainage Function

Brain Mechanisms of COVID-19-Sleep Disorders

“…[138][139][140][141][142][143][144][145]; (D,E) the virus can enter into the brain through the anatomical connection between the meningeal lymphatic vessels and the lymphatic vessels localized along the olfactory nerve [141]. The lymphatic window into the brain is considered in [146][147][148]; (F-H) The SARS-CoV-2 via the ACE2 receptor on the endothelial cells of the lymphatic vessels [149] can enter into the brain tissues inducing cytokine storm (F) and endothelial inflammation that alters the BBB integrity (G) facilitating COVID-19-related sleep disorders (H). SARS-CoV-2 also affects the olfactory centers (olfactory bulb and cortex), thereby reducing smell sensations [150][151][152][153][154][155][156].…”

A review of career devoted to Biophotonics – In memoriam to Ekaterina Borisova (1978–2021)

“…For many years, together with Alexander Priezzhev and Valery Tuchin, Assoc. Prof. Ekaterina Borisova led the Biophotonics section at the world-famous International Conference Laser Optics (ICLO) in St. Petersburg, was the editor of special issues of the world's leading journals in the field of biophotonics and biomedical optics, collaborated with many scientific groups, including several groups at Saratov State University (in addition to the already mentioned joint publications see more [65,68,[87][88][89][90][91][92][93][94][95][96][97][98]), Moscow State University and the Polytechnic of Porto.…”

“…Recently, in Saratov through the efforts of the Institute of Electronics, Bulgarian Academy of Sciences, together with SSU, SSMU, Institute of Biochemistry and Physiology of Plants and Microorganisms and Precision Mechanics and Control Institute of the Russian Academy of Sciences, the development of a new strategy for the combined treatment of a tumor has begun, namely, the plasmon photothermal and photodynamic anticancer therapies using nanocomposites of gold nanoparticles with a novel type photosensitizer. The first results showed the effectiveness of the approach [98], but unfortunately, they were suspended. Ekaterina was the link between scientific groups from Bulgaria and Russia that synthesized agents and nanocomposites and conducted animal tests.…”

“…Russian-Bulgarian collaboration was very productive, including organization of exchange of students, training courses and publication more than 30 articles in the peer review journals (see Refs. [64][65][66][67][68][87][88][89][90][91][92][93][94][95][96][97][98][99]) as well as preparation of several thesis of candidate of science. She kindly allowed us to publish for the first time the maps of autofluorescence emission of normal skin in vivo measured by her in the monograph (Fig.…”

Brain mechanisms of COVID-19-sleep disorders

“…The cribriform plate (B) is a center of the lymphatic pathway of metabolic clearance and is a connective bridge between the cerebral spinal fluid and the cervical lymphatic system) [138-145];(D,E) the virus can enter into the brain through the anatomical connection between the meningeal lymphatic vessels and the lymphatic vessels localized along the olfactory nerve[141]. The lymphatic window into the brain is considered in[146][147][148]; (F-H) The SARS-CoV-2 via the ACE2 receptor on the endothelial cells of the lymphatic vessels[149] can enter into the brain tissues inducing cytokine storm (F) and endothelial inflammation that alters the BBB integrity (G) facilitating COVID-19-related sleep disorders (H). SARS-CoV-2 also affects the olfactory centers (olfactory bulb and cortex), thereby reducing smell sensations[150][151][152][153][154][155][156].…”