Biopesticide development & registration: challenges & strategies

Abstract

United Nations Organization (UNO) has an agenda for 2030 for Sustainable Agriculture Development as a part of Sustainable Development Goals (SDGs). It gives more attention to food security, regarding not only food availability but also food healthy and a friendly environment. A large amount of pesticide usage in the world increased by 36% or 4.2 million tons in the last two decades 2000-2019. Unfortunately, biopesticides as a part of pesticides that contribute to Integrated Pest Management (IPM) and organic farming share only 1-5% of pesticides on the global market, while it is believed to have a good prospect to be used widely in the future. Due to the hazardous and harmful pesticides, the world countries apply regulations and registration to minimize the bad effect of pesticide use but these are varied in many countries. The difference between synthetic chemical pesticides and the biopesticide mode of action should be considered to have fair regulations. On the global market, there are 1400 biopesticides products. Innovation on biopesticides due to control pests as well as facing environmental and health issues is quite developed, however, it has some constraints in certain aspects to increase the use to support sustainable agriculture development, such as variability in knowledge, different regulations in any country, and lack of distribution at the farmer level. To encourage the wide use of biopesticides can be recommended some strategies for the national government (1) cut off the use of chemical pesticides, (2) develop some research for the near future, such as redesigning cropping systems, enhancing prophylaxis, (3) support the development of public policies and private initiatives for the transition toward pesticide-free agri-food systems, (4) reduce some requirements in biopesticide registration such as toxicological tests, environmental tests, residual tests, and acute oral and dermal tests.

Susceptibility of Tetranychus urticae to the Alkaloidal Extract of Zanthoxylum schreberi Bark: Phenotypic and Biochemical Insights for Biotechnological Exploitation

“…Although a biopesticide has a good cost-effectiveness ratio, its production and effective usage necessitate adherence to specific requirements to ensure efficiency, quality, and environmental safety [62]. In addition, notwithstanding their potential benefits, biopesticides have yet to attain the desired level of adoption needed to replace the prevalent use of commercially available synthetic pesticides, constituting a modest fraction of the global crop protection market, comprising just 5% (ca.…”

“…Additionally, a thorough understanding of the target pest and its biology is crucial for designing biopesticides that are not only effective but also selective, minimizing non-target impacts. Hence, successful biopesticide production requires a harmonious integration of scientific equipment, labor, technological to environmental stewardship [62][63][64].…”