Bionic structure and blood compatibility of highly oriented homo-epitaxially crystallized poly(l-lactic acid)

Yang, Wenchao; Wu, Ting; Chen, Yueling; Huang, Qingyang; Ao, Jinqing; Mei, Ming; Gao, Xiaoyan; Li, Zhengqiu; Chen, Baoshu

doi:10.1016/j.ijbiomac.2022.12.192

Cited by 5 publications

(2 citation statements)

References 40 publications

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“…Ultrapure water and PBS were regarded as the positive and negative controls, respectively. The calculation formula for the hemolysis rate was as follows: hemolysis ratio .25em ( % ) = OD t − OD n OD p − OD n × 100 Here, OD t , OD p , and OD n are the absorbances of the treated sample, positive control, and negative control at 541 nm, respectively.…”

Section: Methodsmentioning

confidence: 99%

Nanosilver Embedded in a Magnetosome Nanoflower to Enhance Antibacterial Activity for Wound Dressing Applications

Qi,

Wang,

Wen

et al. 2023

ACS Appl. Mater. Interfaces

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The natural biofilm on magnetosomes obtained from the biomineralization of magnetotactic bacteria, which replaced a complex chemical modification process on the surface of Fe3O4, can be used as the organic component and copper(II) ions as the inorganic component to form organic–inorganic nanoflowers in phosphate systems. Characterization by scanning electron microscopy, Fourier transform infrared spectroscopy, and vibrating-sample magnetometry proved that magnetic nanoflowers loaded with silver ions (Ag/MN-Cu×NFs) were successfully fabricated. In vitro antibacterial experiments demonstrated that Ag/MN-Cu×NFs displayed strong antibacterial effects against Escherichia coli and Staphylococcus aureus, with minimum inhibitory concentrations of 10 and 80 μg/mL, respectively. Ag/MN-Cu×NFs, which possessed good biocompatibility as confirmed by cytotoxicity and hemolysis tests, were able to promote wound healing in the face of bacterial infection in vivo without causing toxicity to major organs. Therefore, magnetosomes as a natural carrier have great application potential in the synthesis of multifunctional magnetosomes by direct hybridization with a target substance.

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Section: Methodsmentioning

confidence: 99%

Nanosilver Embedded in a Magnetosome Nanoflower to Enhance Antibacterial Activity for Wound Dressing Applications

Qi,

Wang,

Wen

et al. 2023

ACS Appl. Mater. Interfaces

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“…To achieve the aforementioned goal, major attention has been shifted to biopolymers as alternatives to petroleum-based plastics. Poly(L-lactic acid) (PLLA) is a semi-crystalline polyester derived from renewable resources like corn, potato, starch and sugarcane [1,2], and the advantages of PLLA, including biodegradability [3], compatibility [4], transparency [5], good processability [6] and non-toxic for the human body and the environment [7], has obtained increasing attention in the fields of disposable products [8], biomedicine [9 -11], electronic device [12 -14], automobile industry [15 -17], For instance, PLLA was used as a base polymer to load and deliver the topical antibiotic, neomycin. The in vitro dissolution firstly exhibited firstorder release kinetics for neomycin, followed by diffusioncontrolled release after releasing for 20 h, and the ability to load neomycin onto PLLA increases threefold with molecular weight of polyethylene glycols coating decreasing from 20 kDa to 400 Da.…”

Section: Introduction mentioning

confidence: 99%

The Nucleated Poly(L-lactic acid): The Role of a Phenylacetic Hydrazide Derivative

TAN,

LV,

HUANG

et al. 2024

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The melt-crystallization, cold-crystallization, melting behaviors, thermal stability, and optical properties of poly(L-lactic acid) (PLLA) nucleated by a phenylacetic hydrazide derivative (DAPH) were investigated. The melt-crystallization confirmed DAPH’s heterogeneous nucleation role in improving PLLA’s poor crystallization capability, concurrently DAPH loading, cooling rate and final melting temperature were three key factors affecting PLLA’s melt-crystallization behaviors. The results from cold-crystallization indicated that the addition of DAPH could accelerate PLLA’s cold-crystallization via cold-crystallization peak’s shift toward the lower temperature side as DAPH loading increased. Through analysis of PLLA/DAPH’s multiple melting behaviors after melt-crystallization, it was found that DAPH loading, the previous melt-crystallization and heating rate determined PLLA/DAPH’s melting processes after melt-crystallization; and PLLA/DAPH’s melting processes after isothermal crystallization depended on the previous crystallization temperature. A drop in thermal decomposition temperature for 5 wt.% mass loss suggested that pure PLLA has better thermal stability compared with PLLA/DAPH. Additionally, the introduction of DAPH could not improve PLLA’s transparency, in contrast, the haze of PLLA was increased greatly owing to the existence of DAPH.

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Hierarchical structure of poly(ε-caprolactone) crystals on its copolymer poly(l-lactide-co-ε-caprolactone) fibers

Chang,

Ren,

Wang

et al. 2024

Applied Surface Science

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Bionic structure and blood compatibility of highly oriented homo-epitaxially crystallized poly(l-lactic acid)

Cited by 5 publications

References 40 publications

Nanosilver Embedded in a Magnetosome Nanoflower to Enhance Antibacterial Activity for Wound Dressing Applications

Nanosilver Embedded in a Magnetosome Nanoflower to Enhance Antibacterial Activity for Wound Dressing Applications

The Nucleated Poly(L-lactic acid): The Role of a Phenylacetic Hydrazide Derivative

Hierarchical structure of poly(ε-caprolactone) crystals on its copolymer poly(l-lactide-co-ε-caprolactone) fibers

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