“…Furthermore, riboflavin is reported to be a potent collagen crosslinking agent due to its lack of toxicity; however, it is more efficient when activated by ultraviolet light, which is not common in all dental clinics [ 10 , 12 , 13 ]. Many studies used Epigallocatechin-3-gallate, present in green tea, as a naturally occurring crosslinker which showed promising results in reducing collagen degradation by MMPs and improving resin-dentin bonded interfaces stability [ 24 – 26 ]. On the other hand, the use of the naturally occurring Salvadora persica as a potential natural crosslinker may provide a great solution for enhancing resin–dentin bond durability; however, its effect on dentinal collagen is not yet fully investigated.…”