Biomineralization synthesis of HBc-CuS nanoparticles for near-infrared light-guided photothermal therapy

Jia, Qingran; Li, Danyang; Zhang, Qiang; Ye, Shefang; Xi, Zhou; Wang, Xiumin; Shan, Wenjun; Ren, Lei

doi:10.1007/s10853-019-03613-6

Cited by 20 publications

(11 citation statements)

References 34 publications

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“…Mammalian viruses have also been utilized in PTT. HBc has been used to encapsulate copper sulfide for PTT only [222], conjugated to a RGD peptide for tumor targeting and loaded with indocyanine green for image-guided PTT [223], and loaded with iron oxide and methotrexate for MRI and PTT [224]. Lastly, ferritin based VLPs have been used to load copper sulfate [225] and gold nanoparticles [226] for cancer theranostics.…”

Section: Photothermal Therapy and Other Theranostic Approachesmentioning

confidence: 99%

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

Chung

Cai

Steinmetz

2020

Advanced Drug Delivery Reviews

281

241

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Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials derived from plant viruses, bacteriophages, and mammalian viruses. The application and development of VNPs and their genomefree versions, the virus-like particles (VLPs), for nanomedicine is a rapidly growing. VLPs can encapsulate a wide range of active ingredients as well as be genetically or chemically conjugated to targeting ligands to achieve tissue specificity. VLPs are manufactured through scalable fermentation or molecular farming, and the materials are biocompatible and biodegradable. These properties have led to a wide range of applications, including cancer therapies, immunotherapies, vaccines, antimicrobial therapies, cardiovascular therapies, gene therapies, as well as imaging and theranostics. The use of VLPs as drug delivery agents is evolving, and sufficient research must continuously be undertaken to translate these therapies to the clinic. This review highlights some of the novel research efforts currently underway in the VNP drug delivery field in achieving this greater goal.

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Section: Photothermal Therapy and Other Theranostic Approachesmentioning

confidence: 99%

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

Chung

Cai

Steinmetz

2020

Advanced Drug Delivery Reviews

281

241

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“…[66] Qingran Jia et al efficiently synthesized CuS nanoparticles with good photothermal conversion efficiency, high cell uptake rate and biocompatibility in the inner lumen of virus-like particles of transgenic hepatitis B core protein (Figure 5C). [67] Summary and comparison of chemical, physical and biosynthesis methods of CuS nanoparticles are shown in Table 4.…”

Section: Physicalmentioning

confidence: 99%

“…efficiently synthesized CuS nanoparticles with good photothermal conversion efficiency, high cell uptake rate and biocompatibility in the inner lumen of virus‐like particles of transgenic hepatitis B core protein (Figure 5C). [67] …”

Section: Preparation Of Copper Based Nanoparticelsmentioning

confidence: 99%

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Copper‐Based Nanoparticles as Antibacterial Agents

Liao

et al. 2022

Eur J Inorg Chem

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Over the past few decades, the resistance of different pathogenic bacteria to various antibiotics has gradually increased. In order to solve the problems of this modern era, metal nanoparticles have attracted more attention than ever. Copper has been recognized as a non-toxic, safe inorganic material and cheap antibacterial or antifungal agent, showing potential antibacterial effect in many biomedical fields. This interest has accelerated the generation of many novel methods for the synthesis of copper-based nanoparticles. Due to the nontoxicity and safety requirements of antibacterial agents, the recent green synthesis of copper-based nanoparticles is gradually replacing the traditional methods. In addition, the antibacterial mechanism of copper-based nanoparticles has provoked great curiosity. This review summarizes the synthetic methods, the possible antibacterial mechanisms and applications of copper-based nanoparticles. Additionally, the application prospects of copper-based nanoparticle antibacterial agent in biomedical applications and clinical field have been described and discussed.

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“…Hence, metallic nanoparticles are no longer used combined with other therapies in clinical trials. Current developments in utilizing biomineralized nanoformulation for sustained and multifaced therapy have opened the gates to the incorporation of new and efficient drug delivery systems for a wide variety of cancer types [133,134]. Biomineralized encapsulation of metal nanoformulations prolongs the half-life in the blood circulation and prevents protein corona formation from reducing the immune response before reaching the target.…”

Section: Limitations and Future Perspectivesmentioning

confidence: 99%

Metallic Nanoparticle-Mediated Immune Cell Regulation and Advanced Cancer Immunotherapy

2021

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Cancer immunotherapy strategies leveraging the body’s own immune system against cancer cells have gained significant attention due to their remarkable therapeutic efficacy. Several immune therapies have been approved for clinical use while expanding the modalities of cancer therapy. However, they are still not effective in a broad range of cancer patients because of the typical immunosuppressive microenvironment and limited antitumor immunity achieved with the current treatment. Novel approaches, such as nanoparticle-mediated cancer immunotherapies, are being developed to overcome these challenges. Various types of nanoparticles, including liposomal, polymeric, and metallic nanoparticles, are reported for the development of effective cancer therapeutics. Metallic nanoparticles (MNPs) are one of the promising candidates for anticancer therapy due to their unique theranostic properties and are thus explored as both imaging and therapeutic agents. In addition, MNPs offer a dense surface functionalization to target tumor tissue and deliver genetic, therapeutic, and immunomodulatory agents. Furthermore, MNPs interact with the tumor microenvironment (TME) and regulate the levels of tumor hypoxia, glutathione (GSH), and reactive oxygen species (ROS) for remodulation of TME for successful therapy. In this review, we discuss the role of nanoparticles in tumor microenvironment modulation and anticancer therapy. In particular, we evaluated the response of MNP-mediated immune cells, such as dendritic cells, macrophages, T cells and NK cells, against tumor cells and analyzed the role of MNP-based cancer therapies in regulating the immunosuppressive environment.

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Biomineralization synthesis of HBc-CuS nanoparticles for near-infrared light-guided photothermal therapy

Cited by 20 publications

References 34 publications

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

Copper‐Based Nanoparticles as Antibacterial Agents

Metallic Nanoparticle-Mediated Immune Cell Regulation and Advanced Cancer Immunotherapy

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