Biomineralization on polymer-coated multi-walled carbon nanotubes with different surface functional groups

Li, Xiaoli; Lan, Jinle; Ai, Miao; Guo, Yougang; Cai, Qing; Yang, Xiaoping

doi:10.1016/j.colsurfb.2014.10.026

Cited by 33 publications

(21 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For the mineralized PLGA scaffold, we can see that Bragg peaks of HAP (25.8, 48.9) and DCP (29.2, 31.6) are appeared in the spectrum. The XRD pattern of the mineralized mPLGA scaffold show that the calcium phosphate coating also possesses components of HAP (25.9, 32.2, 39.8, and 53.3) , and DCP (29.2), but the peaks were sharper and the content of HAP was higher in these mixtures. Nevertheless, the peaks of the coated HAP crystals on the surface of both the scaffolds were comparatively broader and lower, suggesting that the grown HAP crystals had low crystallinity or small crystallite size , as evidenced by the SEM observation.…”

Section: Resultsmentioning

confidence: 99%

Biomineralization improves mechanical and osteogenic properties of multilayer‐modified PLGA porous scaffolds

Kong

Wei

Groth

et al. 2018

J Biomedical Materials Res

View full text Add to dashboard Cite

Poly-(lactide-co-glycolide acid) (PLGA) has been widely investigated as scaffold material for bone tissue engineering owing to its biosafety, biodegradability, and biocompatibility. However, the bioinert surface of PLGA may fail in regulating cellular behavior and directing osteointegration between the scaffold and the host tissue. In this article, oxidized chondroitin sulfate (oCS) and type I collagen (Col I) were assembled onto PLGA surface via layer by layer technique (LbL) as an adhesive coating for the attachment of inorganic minerals. The multilayer-modified PLGA scaffold was mineralized in vitro to ensure the deposition of nanohydroxyapatite (nHAP). It was found that nHAP crystals were more uniformly and firmly attached on the multilayer-modified PLGA as compared with the pure PLGA scaffold, which remarkably improved PLGA surface and mechanical properties. Additionally, in vitro biocompatibility of PLGA scaffold, in terms of bone mesenchymal stem cells (BMSCs) attachment, spreading and proliferation was greatly enhanced by nHAP coating and multilayer deposition. Furthermore, the fabricated composite scaffold also shows the ability to promote the osteogenic differentiation of BMSCs through the up-regulation of osteogenic marker genes. Thus, this novel biomimetic composite scaffold might achieve a desirable therapeutic result for bone tissue regeneration. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 2714-2725, 2018.

show abstract

Section: Resultsmentioning

confidence: 99%

Biomineralization improves mechanical and osteogenic properties of multilayer‐modified PLGA porous scaffolds

Kong

Wei

Groth

et al. 2018

J Biomedical Materials Res

View full text Add to dashboard Cite

show abstract

“…The presence of hydroxyl groups and carbonyl groups corresponds to the appearance of broad peaks at 3425 and 1736 cm −1 , respectively. It should be noted that the presence of hydroxyl and carbonyl groups can enhance the dispersion of CNTs as well as reactivity with other functional groups of polymers [30][31][32][33].…”

Section: Resultsmentioning

confidence: 99%

Synthesis and characterization of nanocomposites based on poly(3-hexylthiophene)-graft-carbon nanotubes with LiNi0.5Mn1.5O4 and its application as potential cathode materials for lithium-ion batteries

Nguyen

et al. 2016

Bull Mater Sci

View full text Add to dashboard Cite

The P3HT grafted on CNTs to form the P3HT-g-CNTs nanocomposites was synthesized and their morphologies, structure have been characterized via the sedimentation test, scanning electron microscopy (SEM), X-ray diffraction (XRD) and transmission electron microscopy (TEM). The results showed that the P3HT-g-CNTs has a better thermal stability than that of the P3HT/CNTs blend. The nanocomposite based on P3HT-g-CNTs and doped spinel LiNi 0.5 Mn 1.5 O 4 (LNMO) have been fabricated via mixing process. The structure and morphologies of LNMO/P3HT-g-CNTs nanocomposites have also been performed by SEM, XRD and TEM. The electrochemical performance of LNMO/P3HT-g-CNTs nanocomposites as cathode materials of lithium-ion batteries were investigated by cyclic voltammetry and electrochemical impedance spectroscopy and exhibited the high diffusion of lithium ions in the charge-discharge process.

show abstract

“…However, the negatively charged ‐COOH in side‐chain of TVH19 was changed to the neutral ‐CONH 2 . Although this change may decrease the growth rate of apatite formation, it was reported to avail to develop c‐axis‐oriented construction, which resembled with the morphology of hydroxyapatite in natural bone tissue (Hosseini et al, ; Li, Lan, et al, ).…”

Section: Discussionmentioning

confidence: 99%

Bifunctional anticaries peptides with antibacterial and remineralizing effects

Wang

et al. 2018

Oral Diseases

View full text Add to dashboard Cite

Objectives Initial dental caries often occurs in clinic. Reduction of cariogenic bacteria and promotion of remineralization are effective ways to control them. This study was to develop bifunctional anticaries peptides with antibacterial and remineralizing properties. Methods We designed peptides TDH19, TNH19, and TVH19 and selected one through comparing their minimal inhibitory concentrations (MICs) and minimal bactericidal concentrations (MBCs) against Streptococcus mutans and their reaction on mineralization. Then the bifunction of the selected peptide was studied through: (a) effects on S. mutans biofilm, (b) remineralizing effects on initial lesions and (c) stability in saliva and cytocompatibility to human oral keratinocytes (HOKs). Results TVH19 showed the lowest MIC and MBC and a better mineralizing ability. It inhibited new biofilm formation and reduced the viability of old biofilm (p < 0.05). Treating initial caries with TVH19 led to greater recovery of surface microhardness, shallower lesion depth, and higher mineral content (p < 0.05). No significant differences were observed between TVH19 and NaF samples (p > 0.05). TVH19 was stable in saliva and had little effect on HOKs. Conclusions The novel bifunctional anticaries peptide TVH19 was developed with remarkable antibacterial activity and the potential to enhance remineralization of initial caries.

show abstract

Biomineralization on polymer-coated multi-walled carbon nanotubes with different surface functional groups

Cited by 33 publications

References 39 publications

Biomineralization improves mechanical and osteogenic properties of multilayer‐modified PLGA porous scaffolds

Biomineralization improves mechanical and osteogenic properties of multilayer‐modified PLGA porous scaffolds

Synthesis and characterization of nanocomposites based on poly(3-hexylthiophene)-graft-carbon nanotubes with LiNi0.5Mn1.5O4 and its application as potential cathode materials for lithium-ion batteries

Bifunctional anticaries peptides with antibacterial and remineralizing effects

Contact Info

Product

Resources

About