Biomimetic zinc(II) and cobalt(II) complexes with tri-tert-butoxysilanethiolate and imidazole ligands – Structural and spectroscopic studies

Synthesis, spectroscopy and crystal structure determination of heteroleptic cobalt(II) silanethiolates with pyridine derivatives

“…For many years, we have been involved in the synthesis of metal silanethiolates with tri-tert-butoxysilanethiol ( t BuO) 3 SiSH as a thiolate ligand [16][17][18][19][20][21][22][23][24][25][26][27][28]. This compound contains a Si-S bond and bulky tri-tert-butoxyl residues, which provide steric hindrance on the sulfur atom, so protecting the silanethiol against hydrolysis.…”

“…Our main interests are related to the synthesis of Co(II) tri-tert-butoxysilanethiolate family complexes, which could serve as alternatives to zinc complexes applicable to spectroscopic studies of metal binding sites in zinc proteins [16][17][18]26]. In this paper, we describe the synthesis, structures and spectroscopic studies of four new Co(II) tri-tert-butoxysilanethiolates with 3-and 4-methylpyridine.…”

Cobalt(II) silanethiolato complexes with dimethylpyridines: crystal structures and spectroscopic studies

“…Relying on our earlier UV-Vis analysis of cobalt(II) silanethiolates with imidazoles as a co-ligand [10], we suppose that such models will be useful for the spectral studies of the active centers of other metalloproteins [10,[15][16][17][18], and this paper is the continuation of our research. Here, we describe the syntheses, structures and spectral analysis of three monomeric new cobalt(II) tri-tert-butoxysilanethiolates with dimethylpyridine co-ligands.…”

“…Generally, silanethiols are sensitive to atmospheric conditions and hydrolyze easily with the evolution of H 2 S. In our syntheses, we use tri-tert-butoxysilanethiol as a source of S-ligand. This sterically hindered compound is resistant to hydrolysis and enables the preparation of monomeric and relatively stable complexes for synthesis conducted under normal atmospheric conditions [6][7][8][9][10].…”

“…Previous results indicate that Co(II) and Zn(II) tri-tert-butoxysilanethiolates show strong correlations with biological systems and imitate the coordination environment of metal-containing proteins like alcohol dehydrogenase ADH, transcription factor TFIIIA or farnesyltransferase FTase, where the metal atom is coordinated by histidines and cysteines [6][7][8][9][10][11][12][13][14].…”