Biomimetic Synthesis of Lamellarin G. Trimethyl Ether

Abstract

references therein. [lo] A linear relation between (l,/Dopl/DJ and A?,,,ax (where D,, and D, are optical and static dielectric constants) has been obtained with a slope of 6200cm.' and an intercept of 5800cm-' [ l l ] S.

Visible-light photoredox catalyzed synthesis of pyrroloisoquinolines via organocatalytic oxidation/[3 + 2] cycloaddition/oxidative aromatization reaction cascade with Rose Bengal

“…Moreover lamellarin I and lamellarin K also showed potential antitumor activities [8–9]. Due to their potential biological activities, the synthesis of pyrrolo[2,1- a ]isoquinolines has become a very interesting, important and attractive goal in organic synthesis [10–20]. For example, dipolar [3 + 2] cycloaddition using azomethine ylides [21] is a powerful class of reactions that permits the synthesis of structural complex molecules in a straightforward way and has been used for the efficient synthesis of this type of compounds [22–26].…”

A Solvent-Induced Reversal of Regioselectivity in the Suzuki Coupling of Pyrrole Esters

“…The plan was then to intercept compound 12, an intermediate in Steglich's synthesis of Lamellarin G trimethyl ether. [9]. (Fig.…”

Synthesis and Biological Activity of Lamellarin Alkaloids: An Overview

“…50 A key intermediate having a 3,4-diarylpyrrole core (83) The synthesis described in Scheme 14 lacks generality to produce naturally occurring lamellarins that have differentially substituted aromatic rings at the 3-and 4-positions of the pyrrole ring. Steglich solved this problem and achieved the first total synthesis of lamellarin L (Scheme 15).…”