Biomimetic synthesis of hybrid hydroxyapatite nanoparticles using nanogel template for controlled release of bovine serum albumin

Qin, Jinli; Zhong, Zhenyu; Ma, Jun

doi:10.1016/j.msec.2016.01.088

Cited by 40 publications

(19 citation statements)

References 38 publications

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“…These materials can be found in gel form or not; the former being widely used because of its similarity to extracellular fluids [348]. The natural polymers used are chitosan [239,[349][350][351], gelatin [241,248,352], alginate [271,346,353], collagen [354,355], cellulose [352,356], and silk fibroin [357,358]. Among the most used synthetics we have poly(vinyl alcohol) (PVA) [241,352,359], poly(methyl methacrylate) (PMMA) [360], polycaprolactone (PCL) [360], polylactic-co-glycolic acid (PLGA) [361], poly(lactic acid)(PLA) [337,362], etc.…”

Section: Scaffolds For Tissue Engineeringmentioning

confidence: 99%

A brief review on hydroxyapatite production and use in biomedicine

et al. 2019

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Hydroxyapatite (HAp) is a bioceramic widely studied due to its chemical similarity with the mineral component of bones. Besides, it is biocompatible, bioactive and thermodynamically stable in the body fluid what poses it as an attractive material for a wide range of applications in the biomedical field. Several efforts have been focused on the synthesis of particles of this material aiming to the precise control of size and morphology, porosity and surface area. HAp is widely used as an implant for bone tissue regeneration, as a coating for metallic implants and in a drug-controlled release. In this sense, the objective of this review is to gather information related to HAp, providing readers with information about synthesis methods, material characteristics and their applications.

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Section: Scaffolds For Tissue Engineeringmentioning

confidence: 99%

A brief review on hydroxyapatite production and use in biomedicine

et al. 2019

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“…3group in the apatite structure was distinguished, including ν 1 (at 962 cm −1 ), ν 2 (at 472 cm −1 ), ν 3 (at 1034 cm −1 and 1107 cm −1 ), and ν 4 (at 564 cm −1 and 602 cm −1 ) [20,21]. Hydroxyapatite is a kind of apatite crystal whose general molecular formula is Me 10 (XO 4 ) 6 Y 2 .…”

Section: Phase Composition and Chemical Structurementioning

confidence: 99%

Effect of the Fluorine Substitution for –OH Group on the Luminescence Property of Eu3+ Doped Hydroxyapatite

et al. 2020

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In this study, different fluoridated hydroxyapatite doped with Eu3+ ion nanoparticles were prepared by the hydrothermal method. The relationship between luminescence enhancement of Eu3+ ions and a fluorine substitution ratio for hydroxyl group in hydroxyapatite was discussed. Moreover, the effect of fluorine substitution for a hydroxyl group on phase composition, crystallinity, and crystal size was studied. Phase composition and chemical structures were identified by X-ray diffraction (XRD) and Fourier Transform Infrared (FT-IR) Spectroscopy analyses. Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) patterns were performed to analyze the morphology and particle size. X-ray Photoelectron Spectroscopy (XPS) patterns were observed to analyze fluorine substitution for the hydroxyl group and chemical state of Eu3+ ions in fluoridated hydroxyapatite. The results of these experiments indicated that the samples with a different fluorine substitution ratio were prepared successfully by maintaining the apatite structure. With an increasing fluorine substitution ratio, the morphology maintained a rod-like structure but the aspect ratio tended to decrease. XPS patterns displayed that the fluorine replaced the hydroxyl group and brought environmental variation. The fluorine ions could affect the crystal field environment and promote luminescence conversion. There was a linear relationship between the fluorine substitution ratio and luminescence enhancement.

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“…These biodegradable polymers can be used for wound management, orthopedic devices, dental applications, cardiovascular applications, drug delivery, and tissue engineering. Both natural and synthetic polymers play essential roles in modern medicine [ [61] , [62] , [63] , [64] ].…”

Section: Introductionmentioning

confidence: 99%

A comprehensive review of biodegradable synthetic polymer-ceramic composites and their manufacture for biomedical applications

Alizadeh-Osgouei

Wen

2019

Bioactive Materials

217

114

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The application of various materials in biomedical procedures has recently experienced rapid growth. One area that is currently receiving significant attention from the scientific community is the treatment of a number of different types of bone-related diseases and disorders by using biodegradable polymer-ceramic composites. Biomaterials, the most common materials used to repair or replace damaged parts of the human body, can be categorized into three major groups: metals, ceramics, and polymers. Composites can be manufactured by combining two or more materials to achieve enhanced biocompatibility and biomechanical properties for specific applications. Biomaterials must display suitable properties for their applications, about strength, durability, and biological influence. Metals and their alloys such as titanium, stainless steel, and cobalt-based alloys have been widely investigated for implant-device applications because of their excellent mechanical properties. However, these materials may also manifest biological issues such as toxicity, poor tissue adhesion and stress shielding effect due to their high elastic modulus. To mitigate these issues, hydroxyapatite (HA) coatings have been used on metals because their chemical composition is similar to that of bone and teeth. Recently, a wide range of synthetic polymers such as poly (l-lactic acid) and poly (l-lactide-co-glycolide) have been studied for different biomedical applications, owing to their promising biocompatibility and biodegradability. This article gives an overview of synthetic polymer-ceramic composites with a particular emphasis on calcium phosphate group and their potential applications in tissue engineering. It is hoped that synthetic polymer-ceramic composites such as PLLA/HA and PCL/HA will provide advantages such as eliminating the stress shielding effect and the consequent need for revision surgery.

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Biomimetic synthesis of hybrid hydroxyapatite nanoparticles using nanogel template for controlled release of bovine serum albumin

Cited by 40 publications

References 38 publications

A brief review on hydroxyapatite production and use in biomedicine

A brief review on hydroxyapatite production and use in biomedicine

Effect of the Fluorine Substitution for –OH Group on the Luminescence Property of Eu3+ Doped Hydroxyapatite

A comprehensive review of biodegradable synthetic polymer-ceramic composites and their manufacture for biomedical applications

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