Biomimetic Structured Porogen Freeform Fabrication System for Tissue Engineering

Zhou, Jack G.; Lü, Lin

doi:10.5772/21551

Cited by 2 publications

(2 citation statements)

References 39 publications

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“…Specifically, we have been investigating the processes of medical bio-scaffolds where cells are implanted in order to adopt the geometry of the scaffold. This process occurs by 3D printing a structure, then seeding it with native cells and proteins to encourage cell adhesion and tissue generation [12]. Being a biocompatible and bioresorbable material [13], the scaffold is designed to degrade over time (see Fig.…”

Section: Medical Bio Scaffoldmentioning

confidence: 99%

Bio Scaffolds

Alima

Snooks

McCormack

2021

Proceedings of the 2021 DigitalFUTURES

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Abstract‘Bio Scaffolds’ explores a series of design tectonics that emerge from a co-creation between human, machine and natural intelligences. This research establishes an integral connection between form and materiality by enabling biological materials to become a co-creator within the design and fabrication process. In this research paper, we explore a hybrid between architectural aesthetics and biological agency by choreographing natural growth through form. ‘Bio Scaffolds’ explores a series of 3D printed biodegradable scaffolds that orchestrate both Mycelia growth and degradation through form. A robotic arm is introduced into the system that can respond to the organism’s natural behavior by injecting additional Mycelium culture into a series of sacrificial frameworks. Equipped with computer vision systems, feedback controls, scanning processes and a multi-functional end-effector, the machine tends to nature by reacting to its patterns of growth, moisture, and color variation. Using this cybernetic intelligence, developed between human, machine, and Mycelium, our intention is to generate unexpected structural and morphological forms that are represented via a series of 3D printed Mycelium enclosures. ‘Bio Scaffolds’ explores an interplay between biological and computational complexity through non anthropocentric micro habitats.

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Section: Medical Bio Scaffoldmentioning

confidence: 99%

Bio Scaffolds

Alima

Snooks

McCormack

2021

Proceedings of the 2021 DigitalFUTURES

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“…This biomimetic corridor, as illustrated in Fig. 4, was used by Zhou and Lu [31] for fabrication of bone scaffolds. Most SFF machines take stereolithography files, and once it is ready, the remaining work is just a matter of printing.…”

Section: Porogen Template Fabricationmentioning

confidence: 99%

Porogen Templating Processes: An Overview

Hong

Zhou

Yao

2014

Journal of Manufacturing Science and Engineering

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Porous materials with wett-defined pore shapes, sizes and distributions are highly desired in many emerging applications, particularly for biomédical materiats and devices. However, conventionat methods for processing porous materiats only demonstrated limited capability in morphological control. One promising solution is the porogen templating process, where a structured porogen pattern is created first and subsequently used as a template or mold for generation of the desired porous material. Particularly, with solid freeform fabrication, porogen temptates having complex internal structures can be additivety fabricated, and they can then be used as motdsfor motding of porous materiats and devices. This articte attempts to offer a constructive overview on the state of the art of porogen patterning and inverse motding, with the goat of exptaining the working mechanisms and providing unbiased accounts of the pros and cons of existing techniques and process variants. The article further intends to provide a fundamental understanding of the constituent elements and corresponding building blocks in porogen templating processes. An increased understanding of these elements will facilitate the development of more capable new processes.

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Biomimetic Structured Porogen Freeform Fabrication System for Tissue Engineering

Cited by 2 publications

References 39 publications

Bio Scaffolds

Bio Scaffolds

Porogen Templating Processes: An Overview

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