Biomimetic Multilayered Lipid Nanovesicles for Potent Protein Vaccination
Bon Il Koo,
Dong Jae Lee,
Rafia Tasnim Rahman
et al.
Abstract:Lipid vesicles are widely used for drug and gene delivery, but their structural instability reduces in vivo efficacy and requires specialized handling. To address these limitations, strategies like lipid cross‐linking and polymer–lipid conjugation are suggested to enhance stability and biological efficacy. However, the in vivo metabolism of these altered lipids remains unclear, necessitating further studies. A new stabilization technique without chemical modification is urgently needed. Here, a bio‐mimetic app… Show more
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