Biomimetic Dissolution: A Tool to Predict Amorphous Solid Dispersions

In Vitro–In Vivo Correlations of Carbamazepine Nanodispersions for Application in Formulation Development

“…Table 1 shows a comparison of the different dissolution tests available for designing an IVIVC method. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] Three correlation levels (A-C) are categorized in United States Pharmacopeia <1088>, with an additional level existing as a combination of levels (multiple C) defined in the FDA guidance. 1,2 The highest level of correlation is level A, which is established through a point-to-point comparison of in vitro dissolution data and in vivo input rates.…”