Biomimetic design of oxidized bacterial cellulose-gelatin-hydroxyapatite nanocomposites

Yang, Ming‐Bo; Zhen, Wenjuan; Chen, Hui; Zhi-hua, Shan

doi:10.1016/s1672-6529(16)60334-7

Cited by 24 publications

(10 citation statements)

References 35 publications

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“…Various types of composites with hydroxyapatite were prepared to remove harmful substances [19], Cr (VI) from aqueous solutions [20], or Ni 2+ and Cd 2+ [21]. Other studies aimed the synthesis of cellulose-polymer-hydroxyapatite composites, the two polymers having synergistically biological activity in the integration of bone implants, as well as chitosan [22], poly-L-lactic acid [23,24] or gelatin [25].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of cellulose acetate-hydroxyapatite micro and nano composites membranes for water purification and biomedical applications

Pandele

Comanici

Carp

et al. 2017

Vacuum

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In this work, we report facile synthesis and characterization of new cellulose acetatehydroxyapatite membranes for water purification and biomedical applications. The membranes were synthesized from a polymer solution in N, N'-dimethylformamide (12% wt.) where different concentrations of hydroxyapatite (1, 2, 4% wt. based on the amount of polymer) were dispersed using sonication. The synthesis of membranes was carried out by precipitation employing phase inversion using deionized water. The morphological and structural characterization of the synthesized membranes was carried out using SEM, EDS and FT-IR. Thermal characterization (TGA & DTG) and water flows analysis of the synthesized membranes was also carried out. The SEM analysis confirmed the presence of hydroxyapatite micro/nanostructured particles in the membrane as well as significant changes in the morphology of the membranes surface. The presence of inorganic compounds was also found to influence the thermal or hydrodynamic properties of the composite membranes,

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Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of cellulose acetate-hydroxyapatite micro and nano composites membranes for water purification and biomedical applications

Pandele

Comanici

Carp

et al. 2017

Vacuum

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“…Here, both o-BNC and an increase in Gel content caused the formation of tiny HAp crystallites in the composite system. The developed o-BNC-HAp/Gel showed higher tensile strength (>0.3 MPa) and complete degradation nearly in 90 days in SBF [119]. BNC/HAp composite scaffold system provides suitable biological affinity, but its wide applicability for bone tissue regeneration is limited due to its low mechanical strength.…”

Section: Bacterial Nanocellulose/polymer/filler-based Biomaterialsmentioning

confidence: 99%

Efficacy of Bacterial Nanocellulose in Hard Tissue Regeneration: A Review

Kumar

Han

2021

Materials

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Bacterial nanocellulose (BNC, as exopolysaccharide) synthesized by some specific bacteria strains is a fascinating biopolymer composed of the three-dimensional pure cellulosic nanofibrous matrix without containing lignin, hemicellulose, pectin, and other impurities as in plant-based cellulose. Due to its excellent biocompatibility (in vitro and in vivo), high water-holding capacity, flexibility, high mechanical properties, and a large number of hydroxyl groups that are most similar characteristics of native tissues, BNC has shown great potential in tissue engineering applications. This review focuses on and discusses the efficacy of BNC- or BNC-based biomaterials for hard tissue regeneration. In this review, we provide brief information on the key aspects of synthesis and properties of BNC, including solubility, biodegradability, thermal stability, antimicrobial ability, toxicity, and cellular response. Further, modification approaches are discussed briefly to improve the properties of BNC or BNC-based structures. In addition, various biomaterials by using BNC (as sacrificial template or matrix) or BNC in conjugation with polymers and/or fillers are reviewed and discussed for dental and bone tissue engineering applications. Moreover, the conclusion with perspective for future research directions of using BNC for hard tissue regeneration is briefly discussed.

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“…Yang et al 112 explored the electro-fenton oxidative electrochemical process to oxidize BNC and prepare hydrogels of gelatin/oxidized BNC and hydroxyapatite. During the electrofenton process, the hydroxyl radical (OH • ) is generated in situ by the cathodic reduction of hydrogen peroxide in a three-electrode cell.…”

Section: Gelatinmentioning

confidence: 99%