Biomimetic Coating of Titanium Surface Using Bioactive Glass Nanoparticles

Gadallah, Maged; Darwish, Rahaf; Alshimy, Ahmed; Gepreel, Mohamed Abdel‐Hady; Marei, Mona K.

doi:10.11607/jomi.9156

Cited by 3 publications

(4 citation statements)

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“…Following the method published by Gadallah et al (23), 70S30C BAG was prepared using modified sol-gel technique. Polyethylene oxide (Sigma-Aldrich, Missouri, United States), urea (Loba Chemie, Mumbai, India), tetramethyl orthosilicate (Sigma-Aldrich, Missouri, United States) and calcium nitrate tetrahydrate (Loba Chemie, Mumbai, India) were added to acetic acid (Sigma-Aldrich, Missouri, United States) aqueous solution (0.01 N), and magnetically stirred (Hotplate and stirrer 1000, Jenway Ltd, United Kingdom) until completely dissolved.…”

Section: Bioactive Glass Preparationmentioning

confidence: 99%

“…Electrophoretic deposition, with some modifications (Fig. 1 A) to the methodology previously published (23), was used to develop a surface coating of 70S30C BAG nanoparticles on dental implants (4.2 x 8 mm, OneQ-SL, Dentis Co. Ltd, Daegu, Korea), of grade 23 titanium (Ti-6Al-4V ELI, Titanium -6% Aluminum -4% Vanadium with extra low interstitials) with sandblasted, large grit, acid-etched (SLA) surface. The coating procedure started with magnetic stirring of 0.5 g BAG nanoparticles in 30 ml absolute ethanol for 5 minutes, then the suspension was agitated in a digital ultrasonic cleaner (CD-4820, Codyson, China) for 10 minutes (Fig.…”

Section: Coating Of Titanium Implants With Bag Nanoparticlesmentioning

confidence: 99%

“…Calcium, on the other hand, increases osteoblast proliferation, differentiation, and extracellular matrix mineralization. (23) After BAG preparation, according to modified sol-gel protocol, it was subsequently milled into nanoparticles using ball milling technique. This economical milling process has been proven by Vafa et al(24) and Ma et al(34) to efficiently turn BAG particles into the nano-scale..…”

Section: Coating Of Titanium Implants With Bag Nanoparticlesmentioning

confidence: 99%

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Surface Nano-Roughness of Bioactive Glass Nanoparticles Coating on Titanium Implants (In-Vitro Study)

Shenoda,

Gadallah,

Marei

et al. 2023

Alexandria Dental Journal

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INTRODUCTION:Titanium is an optimal choice for dental implants. However, lack of surface bioactivity is limiting its use, especially in medically compromised patients, among whom insufficient osseointegration is more prevalent. Coating by bioactive glass can improve their efficacy leading to better implant-to-bone bonding, particularly 70S30C being the most bioactive among the binary calcium silicate glass systems. Nanoparticle coatings induce osteoblastic cell attachment and proliferation, have good affinity to bone and possess stronger interfacial bonding to substrate. OBJECTIVES:The aim of the current study was to develop a surface coating of sol-gel 70S30C bioactive glass nanoparticles on titanium dental implants, and to characterize the resultant coating from the standpoint of nano-roughness. METHODOLOGY: Bioactive glass (BAG) was prepared using modified sol-gel technique, then milled into nanoparticles. Particle size of resultant milled powder was measured by Transmission Electron Microscope. Grit-blasted/acid-etched titanium dental implants were coated with bioactive glass nanoparticles via electrophoretic deposition. Average surface nanoroughness of BAG coated implants was analyzed by Atomic Force Microscope. RESULTS: Bioactive glass nanoparticles showed particle size of <20 nm in diameter. There was statistically insignificant difference in average surface nano-roughness between uncoated and BAG coated implants. Although BAG did not increase the nano-roughness, results ensure that the coating has successfully conformed to and minimally affected grit blasted/acidetched surface of uncoated implants on the nanoscale, originally set by the manufacturer to enhance osseointegration. CONCLUSIONS: Coating titanium implants with 70S30C bioactive glass nanoparticles is attainable via electrophoretic deposition technique, resulting in homogenous coating, yet with no increase in nano-roughness.

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Section: Bioactive Glass Preparationmentioning

confidence: 99%

Section: Coating Of Titanium Implants With Bag Nanoparticlesmentioning

confidence: 99%

Section: Coating Of Titanium Implants With Bag Nanoparticlesmentioning

confidence: 99%

See 1 more Smart Citation

Surface Nano-Roughness of Bioactive Glass Nanoparticles Coating on Titanium Implants (In-Vitro Study)

Shenoda,

Gadallah,

Marei

et al. 2023

Alexandria Dental Journal

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“…A separate group consists of bioactive surface modifications of dental implants [384][385][386][387]. Mainly, various osteoinductive growth factors are used [11,375,388].…”

Section: Biochemical Techniquesmentioning

confidence: 99%

Dental Implants: Modern Materials and Methods of Their Surface Modification

Sotova,

Yanushevich,

Kriheli

et al. 2023

Materials

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The development of dental implantology is based on the detailed study of the interaction of implants with the surrounding tissues and methods of osteogenesis stimulation around implants, which has been confirmed by the increasing number of scientific publications presenting the results of studies related to both the influence of the chemical composition of dental implant material as well as the method of its surface modification on the key operational characteristics of implants. The main materials for dental implant manufacturing are Ti and its alloys, stainless steels, Zr alloys (including ceramics based on ZrO2), and Ta and its alloys, as well as other materials (ceramics based on Al2O3, Si3N4, etc.). The review presents alloy systems recommended for use in clinical practice and describes their physical–mechanical and biochemical properties. However, when getting into the body, the implants are subjected to various kinds of mechanical influences, which are aggravated by the action of an aggressive biological environment (electrolyte with a lot of Cl− and H+); it can lead to the loss of osteointegration and to the appearance of the symptoms of the general intoxication of the organism because of the metal ions released from the implant surface into the biological tissues of the organism. Since the osteointegration and biocompatibility of implants depend primarily on the properties of their surface layer (it is the implant surface that makes contact with the tissues of the body), the surface modification of dental implants plays an important role, and all methods of surface modification can be divided into mechanical, physical, chemical, and biochemical methods (according to the main effect on the surface). This review discusses several techniques for modifying dental implant surfaces and provides evidence for their usefulness.

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