Biomimetic biocompatible ferroelectric polymer materials with an active response for implantology and regenerative medicine

Градов, О.В.; Gradova, Margaret A.; Kochervinskiĭ, V. V.

doi:10.1016/b978-0-12-821551-7.00012-9

Cited by 6 publications

(5 citation statements)

References 374 publications

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“…Since the introduction of TPP into the film leads to an increase in the conductivity, which can be controlled by the field, there is potentially a new area of application of such polymers in practical biomedicine. While previously the perspectives of their use in regulating the characteristics of biocompatible materials through the bound charges were discussed [ 10 ], now there are new perspectives of their use by regulating their properties related to the presence of the (quasi-free) carriers.…”

Section: Resultsmentioning

confidence: 99%

“…Ferroelectric polymers are also widely applied for the design of the novel flexible electronic devices for energy storage and conversion [ 4 , 5 ]. In addition to the technical applications, such polymers are also biocompatible, and may be used as various kinds of biosensors [ 6 , 7 , 8 , 9 ], implantable materials, and scaffolds for tissue engineering and regenerative medicine [ 10 ]. This problem is also of great importance, since ferroelectrics, as a class of materials, are actively used in biomedical research [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Optical and Electrophysical Properties of Vinylidene Fluoride/Hexafluoropropylene Ferroelectric Copolymer Films: Effect of Doping with Porphyrin Derivatives

Kochervinskiĭ¹,

Gradova

Градов

et al. 2023

Nanomaterials

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Polymer films doped by different porphyrins, obtained by crystallization from the acetone solutions, differ in absorption and fluorescence spectra, which we attribute to the differences in the structuring and composition of the rotational isomers in the polymer chains. According to the infrared spectroscopy data, the crystallization of the films doped with tetraphenylporphyrin (TPP) proceeds in a mixture of α- and γ-phases with TGTG− and T3GT3G− conformations, respectively. Three bonds in the planar zigzag conformation ensures the contact of such segments with the active groups of the porphyrin macrocycle, significantly changing its electronic state. Structuring of the films in the presence of TPP leads to an increase in the low-voltage AC-conductivity and the registration of an intense Maxwell-Wagner polarization. An increased conductivity by an order of magnitude in TPP-doped films was also observed at high-voltage polarization. The introduction of TPP during the film formation promotes the displacement of the chemical attachment defects of “head-to-head” type in the monomeric units into the surface. This process is accompanied by a significant increase in the film surface roughness, which was registered by piezo-force microscopy. The latter method also revealed the appearance of hysteresis phenomena during the local piezoelectric coefficient d33 measurements.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optical and Electrophysical Properties of Vinylidene Fluoride/Hexafluoropropylene Ferroelectric Copolymer Films: Effect of Doping with Porphyrin Derivatives

Kochervinskiĭ¹,

Gradova

Градов

et al. 2023

Nanomaterials

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“…In the case of ionic or proton conductivity, rather than the conventional charge wandering, this system can be considered as a quasi-chemical ion-exchange system [124] . The effects of ionic conduction can be of great importance for biomedical iontronics and the creation of active implants, which can be stimulated and perform ion exchange with the environment during conduction of biological autowaves and chemical oscillations (for example, in cardiomyocytes and neuronal fibers) [125][126][127][128] . Moreover, despite the apparent homogeneity of the fibers, in fact they can be microheterogeneous, which corresponds to a different surface distribution of the charge/electric double layer.…”

Section: Results and Prospectsmentioning

confidence: 99%

Reaction-diffusion effects and spatiotemporal oscillations under SEM, STM and AFM-assisted charging in fiber-like and wire-like systems: From molecular and quantum wires to cooperative ferroelectric nanofibers and microfibers

Adamovich,

Buryanskaya,

Gradova

et al. 2023

Mater. Tech. Rep.

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This review addresses the problem of reaction-diffusion effects and spatiotemporal oscillations in fiber-like and wire-like systems under the electron beam in SEM and in the presence of electric field in some special AFM techniques, such as current sensing atomic force microscopy (CS-AFM)/conductive atomic force microscopy (C-AFM), electrostatic force microscopy (EFM) and Kelvin probe force microscopy (KPFM) also known as surface potential microscopy. Some similar reaction-diffusion effects also can be observed in scanning capacitance microscopy (SCM), scanning gate microscopy (SGM), scanning voltage microscopy (SVM) and piezoresponse force microscopy (PFM). At the end of this paper the authors provide analysis of their own results and approaches. In particular, the possibility of achieving the ion transfer controlled growth of cells along the ion concentration gradients in reaction-diffusion fibers and actuators is indicated. This fundamental idea is discussed within the framework of the implantable fiber “bioiontronics” and “neuroiontronics” controlled by acoustic and electrical signals that regulate the reaction-diffusion or chemical oscillation activity of such fiber structures as reaction-diffusion actuators and sensors. The literature review includes more than 130 references.

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“…One such class of promising OCMs for next-generation flexible electronics is ferroelectric polymers (a relatively new class of electroactive materials based on copolymers of PVDF and some nylons) [ 3 ]. At present, these materials are being actively studied and find application in various fields of science and technology: as piezo sensors [ 4 , 5 ], biocompatible prosthetic materials, nanogenerators/sensors [ 6 , 7 , 8 ], and adaptive optical system elements [ 8 , 9 , 10 , 11 ]. In contrast to traditional piezoelectrics based on oxide ceramics (PZT, quartz, lithium niobate, etc.…”

Section: Introductionmentioning

confidence: 99%

Structure and Thermomechanical Properties of Polyvinylidene Fluoride Film with Transparent Indium Tin Oxide Electrodes

et al. 2023

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This paper is devoted to the study of the structure and thermomechanical properties of PVDF-based ferroelectric polymer film. Transparent electrically conductive ITO coatings are applied to both sides of such a film. In this case, such material acquires additional functional properties due to piezoelectric and pyroelectric effects, forming, in fact, a full-fledged flexible transparent device, which, for example, will emit a sound when an acoustic signal is applied, and under various external influences can generate an electrical signal. The use of such structures is associated with the influence of various external influences on them: thermomechanical loads associated with mechanical deformations and temperature effects during operation, or when applying conductive layers to the film. The article presents structure investigation and its change during high-temperature annealing using IR spectroscopy and comparative results of testing a PVDF film before and after deposition of ITO layers for uniaxial stretching, its dynamic mechanical analysis, DSC, as well as measurements of the transparency and piezoelectric properties of such structure. It is shown that the temperature-time mode of deposition of ITO layers has little effect on the thermal and mechanical properties of PVDF films, taking into account their work in the elastic region, slightly reducing the piezoelectric properties. At the same time, the possibility of chemical interactions at the polymer–ITO interface is shown.

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Biomimetic biocompatible ferroelectric polymer materials with an active response for implantology and regenerative medicine

Cited by 6 publications

References 374 publications

Optical and Electrophysical Properties of Vinylidene Fluoride/Hexafluoropropylene Ferroelectric Copolymer Films: Effect of Doping with Porphyrin Derivatives

Optical and Electrophysical Properties of Vinylidene Fluoride/Hexafluoropropylene Ferroelectric Copolymer Films: Effect of Doping with Porphyrin Derivatives

Reaction-diffusion effects and spatiotemporal oscillations under SEM, STM and AFM-assisted charging in fiber-like and wire-like systems: From molecular and quantum wires to cooperative ferroelectric nanofibers and microfibers

Structure and Thermomechanical Properties of Polyvinylidene Fluoride Film with Transparent Indium Tin Oxide Electrodes

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