Biomedical Application of Decellularized Scaffolds

Zhang, Fang; Gao, Huimin; Jiang, Xuefeng; Yang, Fang; Zhang, Jun; Song, Saijie; Shen, Jian

doi:10.1021/acsabm.3c00778

ACS Appl. Bio Mater.

2023

DOI: 10.1021/acsabm.3c00778

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Biomedical Application of Decellularized Scaffolds

Fang Zhang,

Huimin Gao,

Xuefeng Jiang

et al.

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2024

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References 312 publications

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Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Liu,

Song,

Yin

et al. 2024

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Decellularized extracellular matrix (dECM) offers a three‐dimensional, non‐immunogenic scaffold, enriched with bioactive components, making it a suitable candidate for tissue regeneration. Although dECM‐based scaffolds have been successfully implemented in preclinical and clinical settings within tissue engineering and regenerative medicine, the mechanisms of tissue remodeling and functional restoration are not fully understood. This review critically assesses the state‐of‐the‐art in dECM scaffolds, including decellularization techniques for various tissues, quality control and cross‐linking. It highlights the functional properties of dECM components and their latest applications in multiorgan tissue engineering and biomedicine. Additionally, the review addresses current challenges and limitations of decellularized scaffolds and offers perspectives on future directions in the field.

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Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Liu,

Song,

Yin

et al. 2024

Exploration

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Biomedical Application of Decellularized Scaffolds

Cited by 1 publication

References 312 publications

Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

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