Biomechanics of stomach tissues and structure in patients with obesity

Carniel, Emanuele Luigi; Albanese, Alessio; Fontanella, Chiara Giulia; Pavan, Piero G.; Prevedello, Luca; Salmaso, C.; Todros, Silvia; Toniolo, Ilaria; Foletto, Mirto

doi:10.1016/j.jmbbm.2020.103883

Cited by 19 publications

(20 citation statements)

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“…Each end of the sample was glued between two patches of balsa wood to prevent any slippage [30,31], clamped by the grips and then hydrated by dropping the PBS on the sample surface for the entire duration of the test (Figure 1b). A gauge length of 15 mm was selected to ensure a mean aspect ratio (length/width) of about 3, in accordance with other test protocols [8,32].…”

Section: Mechanical Testingmentioning

confidence: 99%

Experimental Analysis of Plantar Fascia Mechanical Properties in Subjects with Foot Pathologies

et al. 2021

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Plantar Fascia (PF) is a fibrous tissue that plays a key role in supporting the foot arch; it can be affected by several pathologies that can alter foot biomechanics. The present study aims at investigating the mechanical behavior of PF and evaluating possible correlations between mechanical properties and specific pathologies, namely diabetes and plantar fibromatosis (Ledderhose syndrome). PF samples were obtained from 14 human subjects, including patients with Ledderhose syndrome, patients affected by diabetes and healthy subjects. Mechanical properties of PF tissues were evaluated on three samples from each subject, by cyclic uniaxial tensile tests up to 10% of maximum strain and stress relaxation tests for 300 s, in hydrated conditions at room temperature. In tensile tests, PF exhibits non-linear stress–strain behavior, with a higher elastic modulus (up to 25–30 MPa) in patients affected by Ledderhose syndrome and diabetes with respect to healthy subjects (elastic modulus 10 ÷ 14 MPa). Stress-relaxation tests show that PF of patients affected by Ledderhose syndrome and diabetes develop more intense viscous phenomena. The results presented in this work represent the first experimental data on the tensile mechanical propertied of PF in subjects with foot diseases and can provide an insight on foot biomechanics in pathological conditions.

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Section: Mechanical Testingmentioning

confidence: 99%

Experimental Analysis of Plantar Fascia Mechanical Properties in Subjects with Foot Pathologies

et al. 2021

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“…From each test, experimental force-time data, depending on the assumed strain history (Fig. 6c), were postprocessed by using a low-pass filtering procedure and a 0.02 N cutting force value was assumed by considering the load-cell sensitivity [40]. Force was then converted to stress, as the ratio between force and initial cross-sectional area of the specimen.…”

Section: Mechanical Testsmentioning

confidence: 99%

Mechanical behaviour of healthy versus alkali-lesioned corneas by a porcine organ culture model

et al. 2021

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Background Cornea is a composite tissue exhibiting nonlinear and time-dependent mechanical properties. Corneal ulcers are one of the main pathologies that affect this tissue, disrupting its structural integrity and leading to impaired functions. In this study, uniaxial tensile and stress-relaxation tests are developed to evaluate stress-strain and time-dependent mechanical behaviour of porcine corneas. Results The samples are split in two groups: some corneas are analysed in an unaltered state (healthy samples), while others are injured with alkaline solution to create an experimental ulcer (lesioned samples). Furthermore, within each group, corneas are examined in two conditions: few hours after the enucleation (fresh samples) or after 7 days in a specific culture medium for the tissue (cultured samples). Finally, another condition is added: corneas from all the groups undergo or not a cross-linking treatment. In both stress-strain and stress-relaxation tests, a weakening of the tissue is observed due to the imposed conditions (lesion, culture and treatment), represented by a lower stiffness and increased stress-relaxation. Conclusions Alkali-induced corneal stromal melting determines changes in the mechanical response that can be related to a damage at microstructural level. The results of the present study represent the basis for the investigation of traditional and innovative corneal therapies.

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“…Where r is the quantity that is based on coefficient of determination (R 2 ) and is expressed in Equation (5). The rminimum and rmaximum values are minimum r value for worst hyperelastic model and maximum r value for best hyperelastic model, respectively.…”

Section: Evaluation Index (Ei) Of the Capability Of Anisotropic Hyperelastic Modelsmentioning

confidence: 99%

“…A biomechanical approach can be useful to investigate the stomach mechanical functionality [4]. The development of a computational model of the stomach can allow to examine in depth its functioning, related with complex neuro-gastrointestinal phenomena [5]. Models definition requires experimentations to characterise the organ geometrical conformation and the tissues mechanical behavior as such it is paramount to investigate the mechanical properties of omasum [6].…”

Section: Introductionmentioning

confidence: 99%

Biomechanical behaviour and hyperelastic model parameters identification of sheep omasum

Lebea

Ngwangwa

Pandelani

et al. 2021

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The function of the omasum is incompletely understood; however, the omasum plays an important role in the transport of appropriately sized feed particles from the reticulorumen to the abomasum, oesophageal groove closure, fermentation of ingesta, and absorption of water, volatile fatty acids, and minerals. The aim of this study is to evaluate the suitable hyperelastic anisotropic model based on biomechanical properties of sheep omasum. The results show that all five (5) hyperelastic models may be suitable for the evaluation of sheep omasum. The average coefficient of determination (R2) of Fung, Polynomial (Anisotropic), Holzapfel (2000), Holzapfel (2005) and Four-Fiber-Family hyperelastic models were found to be 0.79 ± 0.19, 0.95 ± 0.05, 0.92 ± 0.07, 0.93 ± 0.05 and 0.94 ± 0.03, respectively. Also, it was found that the best hyperelastic model for fitting uniaxial data of the sheep omasum was Polynomial (Anisotropic) with EI of 100.0 followed by the Four-Fiber-Family model with EI of 96.18.

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Biomechanics of stomach tissues and structure in patients with obesity

Cited by 19 publications

References 50 publications

Experimental Analysis of Plantar Fascia Mechanical Properties in Subjects with Foot Pathologies

Experimental Analysis of Plantar Fascia Mechanical Properties in Subjects with Foot Pathologies

Mechanical behaviour of healthy versus alkali-lesioned corneas by a porcine organ culture model

Biomechanical behaviour and hyperelastic model parameters identification of sheep omasum

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