Biomechanical study of the male lower urinary tract: Simulation of internal and external sphincters dyssynergia

Mechanical Characterization of the Male Lower Urinary Tract: Comparison among Soft Tissues from the Same Human Case Study

“…Currently, this case study sets the basis for the investigation approach for future developments which would require the extension of the numerosity of the population samples to improve the experimental data reliability. Characterization of the essential mechanical properties of the LUT may represent a key aspect for the development of effective in silico models to extend the experimental results to high-level scenarios providing additional information on LUT dysfunctions and reliable diagnostic and/or therapeutic tools for the urological clinical and surgical context [26][27][28]. The study and validation process of innovative procedures and devices for the treatment of LUT pathologies, such as balloon catheters for dilating urethral strictures or artificial sphincters for restoring urinary continence condition [29][30][31][32][33], needs to be considered according to the mechanical behavior of the biological tissues and structures involved, as well as the development and suitability of phantoms mimicking the tissue performance for surgical planning and training [34] and the tissue engineering for surgical reconstruction of anatomical or functional defects [35,36].…”