Purpose: To compare the biomechanical properties of high-tensile strength tape and a high-tensile strength suture in subpectoral biceps tenodesis using a suture anchor in a porcine tendon model. Methods: A total of 24 artificial composite (polymer and glass fiber) humeri and porcine flexor profundus tendons were used. Two types of suture materials, hightensile strength sutures (group S) and high-tensile strength tapes (group T), were evaluated. After we inserted metallic suture anchors with either 2 sutures or tapes 5 cm from the superomedial corner of the greater tuberosity, a Krackow suture technique was used to secure the tendons. After a preload of 5 N for 2 minutes, a cyclic loading test from 5 to 70 N was conducted for 500 cycles. Finally, the specimen was loaded to failure at a rate of 1 mm/s. Results: There were no significant between-group differences in elongation after cyclic loading and elongation at failure load for group S and group T (P ¼ .977 and .630, respectively). The ultimate failure loads in group T (278.2 AE 54 N) were significantly greater than those in group S (249.4 AE 32 N) (P ¼ .028). In contrast, the stiffness values in group T (28.5 AE 4.0 N/mm) were significantly lower than those in group S (32.3 AE 4.5 N) (P ¼ .028). Ten specimens in group S and 8 specimens in group T failed, with tendons being cut through by the sutures, whereas the other 2 specimens in group S and 4 specimens in group T failed due to suture breakage. Conclusions: Using high-tensile strength tapes in subpectoral biceps tenodesis using a suture anchor leads to significantly greater ultimate failure load as compared with using high-tensile strength sutures in a porcine model. Although lower levels of stiffness were found in high-tensile strength tape group, the difference in the means were not large between 2 groups. Clinical Relevance: A strong sutureetendon structure may prevent clinical failure of a subpectoral biceps tenodesis using a suture anchor.