Biomechanical musculoskeletal models of the cervical spine: A systematic literature review

Alizadeh, Mina; Knapik, Gregory G.; Mageswaran, Prasath; Mendel, Ehud; Bourekas, Eric C.; Marras, William S.

doi:10.1016/j.clinbiomech.2019.10.027

Cited by 32 publications

(32 citation statements)

References 61 publications

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“…Those studies show that the results agree well with in vitro measurements. In common, however, implicit FE models usually neglect probable in vivo influences of muscle forces and body weight [55,[60][61][62] and simplify them by a compressive follower load (FL) combined with a pure moment [57,[63][64][65][66][67]. The FL is a force that follows the lumbar lordosis and approximately passes in the sagittal plane through the vertebral body centers, resulting in minimal rotations of the vertebrae and preventing the spine from buckling under high compression [14].…”

Section: Introductionmentioning

confidence: 99%

“…The FL is a force that follows the lumbar lordosis and approximately passes in the sagittal plane through the vertebral body centers, resulting in minimal rotations of the vertebrae and preventing the spine from buckling under high compression [14]. Due to this idealization, shear force components and sagittal compression variations caused by partially high muscle forces cannot be examined [68].The consideration of numerous (passive) deformable components as well as contact problems contribute to an increased computational effort in implicit FE simulations and unfortunately often limit the computational scope to static, quasi-static or only short simulation sequences [39,60,62,69].…”

Section: Introductionmentioning

confidence: 99%

“…Hybrid FE-MB model simulations are a hitherto less established way to overcome the drawbacks of musculoskeletal MB and implicit FE models without couplings. Passive hybrid models are characterized by the combination of rigid and elastic FE bodies and by the fact that even complex biomechanical systems with soft tissues requiring large deformations can be dynamically calculated with great computational efficiency [38,60,73,74]. Current passive hybrid models of the lumbar spine have been built in explicit FE environments (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…The current motivation for hybrid spine modeling is primarily the reduction of computational time, with the resulting advantages for a simplified model structure and increased usability in clinical routine [69, 75-77, 80, 81]. If a hybrid model also includes force actuators (muscles), it can be called an active hybrid model [60]. In other biomechanical research fields, the advantages of active hybrid models are often used, for example, in knee [73,82] or jaw-tongue-hyoid language simulations [74].…”

Section: Introductionmentioning

confidence: 99%

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Calibration and validation of a novel hybrid model of the lumbosacral spine in ArtiSynth–The passive structures

et al. 2021

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In computational biomechanics, two separate types of models have been used predominantly to enhance the understanding of the mechanisms of action of the lumbosacral spine (LSS): Finite element (FE) and musculoskeletal multibody (MB) models. To combine advantages of both models, hybrid FE-MB models are an increasingly used alternative. The aim of this paper is to develop, calibrate, and validate a novel passive hybrid FE-MB open-access simulation model of a ligamentous LSS using ArtiSynth. Based on anatomical data from the Male Visible Human Project, the LSS model is constructed from the L1-S1 rigid vertebrae interconnected with hyperelastic fiber-reinforced FE intervertebral discs, ligaments, and facet joints. A mesh convergence study, sensitivity analyses, and systematic calibration were conducted with the hybrid functional spinal unit (FSU) L4/5. The predicted mechanical responses of the FSU L4/5, the lumbar spine (L1-L5), and the LSS were validated against literature data from in vivo and in vitro measurements and in silico models. Spinal mechanical responses considered when loaded with pure moments and combined loading modes were total and intervertebral range of motions, instantaneous axes and centers of rotation, facet joint contact forces, intradiscal pressures, disc bulges, and stiffnesses. Undesirable correlations with the FE mesh were minimized, the number of crisscrossed collagen fiber rings was reduced to five, and the individual influences of specific anatomical structures were adjusted to in vitro range of motions. Including intervertebral motion couplings for axial rotation and nonlinear stiffening under increasing axial compression, the predicted kinematic and structural mechanics responses were consistent with the comparative data. The results demonstrate that the hybrid simulation model is robust and efficient in reproducing valid mechanical responses to provide a starting point for upcoming optimizations and extensions, such as with active skeletal muscles.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Calibration and validation of a novel hybrid model of the lumbosacral spine in ArtiSynth–The passive structures

et al. 2021

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“…MBMs were the most commonly used, followed by hybrid models and then FEMs. They suggested that in this case, the main limitation was the lack of detail in the musculature modelling 17 . Both reviews identified greater personalisation of models, and the use of patient‐specific electromyogram (EMG) and kinematic data, as promising areas of future work 16,17 .…”

Section: Introductionmentioning

confidence: 99%

Computational modelling of the scoliotic spine: A literature review

Gould¹,

Cristofolini

Davico³

et al. 2021

Numer Methods Biomed Eng

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Scoliosis is a deformity of the spine that in severe cases requires surgical treatment. There is still disagreement among clinicians as to what the aim of such treatment is as well as the optimal surgical technique. Numerical models can aid clinical decision‐making by estimating the outcome of a given surgical intervention. This paper provided some background information on the modelling of the healthy spine and a review of the literature on scoliotic spine models, their validation, and their application. An overview of the methods and techniques used to construct scoliotic finite element and multibody models was given as well as the boundary conditions used in the simulations. The current limitations of the models were discussed as well as how such limitations are addressed in non‐scoliotic spine models. Finally, future directions for the numerical modelling of scoliosis were addressed.

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Basic Biomechanics and Workplace Design

Marras

Karwowski

2021

Handbook of Human Factors and Ergonomics

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Biomechanical musculoskeletal models of the cervical spine: A systematic literature review

Cited by 32 publications

References 61 publications

Calibration and validation of a novel hybrid model of the lumbosacral spine in ArtiSynth–The passive structures

Calibration and validation of a novel hybrid model of the lumbosacral spine in ArtiSynth–The passive structures

Computational modelling of the scoliotic spine: A literature review

Basic Biomechanics and Workplace Design

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