Biomechanical Motion‐Activated Endogenous Wound Healing through LBL Self‐Powered Nanocomposite Repairer with pH‐Responsive Anti‐Inflammatory Effect

Abstract

infection from secondary stripping. In brief, as a pluripotential medical dressing sensor, the HAP/SN-NR has a promising future in various applications, especially tissue repair.

Injectable Hydrogel Based on Defect‐Rich Multi‐Nanozymes for Diabetic Wound Healing via an Oxygen Self‐Supplying Cascade Reaction

“…[32,33] New chemical shifts at 4.82, 4.99, and 5.09 ppm occurred in ODex due to the presence of aldehydes. [34,35] The covalent Schiff base network endows the hydrogel with excellent tissue adhesion capacity, [36,37] enabling the formation of a physical barrier to prevent bacterial invasion and maintain a moist environment to promote wound healing. [38] The hydrogel can strongly adhere to freely bent finger joints and twisted porcine skin (Figure 2b,c).…”

Bioactive hydrogels based on polysaccharides and peptides for soft tissue wound management

“…Benefit from the strong hygroscopicity and abundant internal space, chitosan-based hydrogels can also absorb contaminants from wound effusion. Further antimicrobial-enhanced chemical modification (such as quaternary ammonium, 30,35,[37][38][39][40][41][42][43] alkylate [44][45][46] and antibacterial peptide 41,47 ) and physical encapsulation (such as antibiotics, 31,32,45,47 polydopamine, 38,42,48 graphene oxide, 30,38,49 carbon nanotubes 50 and other nanomaterials 37,42,45,48,51 ) methods are also favorable.…”

ADSC-exo@MMP-PEG smart hydrogel promotes diabetic wound healing by optimizing cellular functions and relieving oxidative stress

“…Smart hydrogel, with the identities of traditional hydrogel, could react to certain stimulus, e. g. temperature, enzyme or reactive oxygen species (ROS) [ [26] , [27] , [28] , [29] ]. Some researches indicated that smart hydrogel could heal the wound better due to its stimuli-responsive ability and drug delivery capacity [ [29] , [30] , [31] , [32] , [33] ]. These characteristics make smart hydrogel suitable for loading exosome.…”