Biomechanical characteristics of regenerated cortical bone in the canine mandible

Zapata, Uriel; Opperman, Lynne A.; Kontogiorgos, Elias; Elsalanty, Mohammed; Dechow, Paul C.

doi:10.1002/term.347

Cited by 5 publications

(11 citation statements)

References 40 publications

(41 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This surgical process has been widely used not only because it has been shown that the quality of the new cortical bone created during the BTDO procedure resembles the original bone [26,31,32], but also because it allows early implants placement induced by the functional recovery of the mandible [33,34]. The present article provides evidence for a couple of biomechanical benefits of the mandibular BTDO process.…”

Section: Discussionmentioning

confidence: 86%

“…A previous study from the authors reported the mechanical properties of the regenerate dog cortical bone are not only heterogeneous, but also tend to be approximately transversely isotropic at a tissue level as opposed to control cortical bone that is orthotropic [26]. Isotropic elastic moduli of the dog trabecular bone were obtained from the ultrasonic test of the femora of eight dogs [25].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Biomechanics of the Canine Mandible During Bone Transport Distraction Osteogenesis

Zapata

Dechow

Watanabe

et al. 2014

Journal of Biomechanical Engineering

Self Cite

View full text Add to dashboard Cite

This study compared biomechanical patterns between finite element models (FEMs) and a fresh dog mandible tested under molar and incisal physiological loads in order to clarify the effect of the bone transport distraction osteogenesis (BTDO) surgical process. Three FEMs of dog mandibles were built in order to evaluate the effects of BTDO. The first model evaluated the mandibular response under two physiological loads resembling bite processes. In the second model, a 5.0 cm bone defect was bridged with a bone transport reconstruction plate (BTRP). In the third model, new regenerated bony tissue was incorporated within the defect to mimic the surgical process without the presence of the device. Complementarily, a mandible of a male American foxhound dog was mechanically tested in the laboratory both in the presence and absence of a BTRP, and mechanical responses were measured by attaching rosettes to the bone surface of the mandible to validate the FEM predictions. The relationship between real and predicted values indicates that the stress patterns calculated using FEM are a valid predictor of the biomechanics of the BTDO procedures. The present study provides an interesting correlation between the stiffness of the device and the biomechanical response of the mandible affected for bone transport.

show abstract

Section: Discussionmentioning

confidence: 86%

Section: Methodsmentioning

confidence: 99%

Biomechanics of the Canine Mandible During Bone Transport Distraction Osteogenesis

Zapata

Dechow

Watanabe

et al. 2014

Journal of Biomechanical Engineering

Self Cite

View full text Add to dashboard Cite

show abstract

“…A higher elastic modulus of cortical bone on the lingual side of the dog mandible was also found [32]. In humans, the buccal mandible hardness was found to be higher than in the maxilla [21].…”

Section: Discussionmentioning

confidence: 99%

Can cone beam CT predict the hardness of interradicular cortical bone?

et al. 2014

View full text Add to dashboard Cite

ObjectivesOrthodontic mini implants can be inserted at the interradicular site. The bone quality at this site may affect the stability and anchorage of the implant. Bone density is clinically evaluated by Hounsfield units (HU) obtained from cone beam CT (CBCT). The objective of this study was to determine the correlations between HU, microhardness and cortical bone thickness of interradicular site at various segments (anterior/posterior) and aspects (buccal/lingual) of both jaws in a swine model.Materials and methodsEight mandible and maxilla swine bones were scanned by CBCT. The HU and thickness of the above-mentioned sites were determined. Then, a Knoop microhardness test was applied and the Knoop Hardness Number was obtained (KHN).ResultsThe mandible parameters spread over a wider range than the maxilla. The buccal aspect of the maxilla had higher HU and KHN values than the mandible. The lingual aspect of the mandible had higher KHN values than the maxilla. Posterior segments had higher HU and KHN values. The thickness of the alveolar cortical bone was greater in the maxilla than in the mandible. Correlations were found between HU and KHN for 3 of the 4 sites (anterior or posterior, buccal or lingual) of the mandible only. No correlations were found for the maxilla. Upon pooling the HU and KHN data for the whole jaw, correlation was found for the maxilla as well.ConclusionsRelying on HU values as a predictor of cortical bone hardness should be considered with caution.

show abstract

“…Cortical bone apparent density (mg/cm 3 ) was calculated from the sample weight by using an analytical balance (PM460, Mettler-Toledo International INC, Columbus, OH, USA) and differential volume in water, based on Archimedes’ principle of buoyancy [27]. In addition, elastic mechanical properties were obtained for all specimens using an ultrasound test technique [16]. The direction of maximum strength was obtained with respect to the original reference line, and it was marked on the specimen by two notches that were clearly observed during three dimensional μ-CT reconstructions (Fig.…”

Section: Methodsmentioning

confidence: 99%

“…Although the biomechanical characteristics of the new bony tissue generated after DO have been addressed in different studies [12–15], only one previous study has focused on the mechanical properties of the new bone formed after BTDO [16], which showed a direct relationship between mechanical properties of cortical bone and its microstructure similar to Curry [17]. …”

Section: Introductionmentioning

confidence: 99%

Architecture and Microstructure of Cortical Bone in Reconstructed Canine Mandibles After Bone Transport Distraction Osteogenesis

et al. 2011

Self Cite

View full text Add to dashboard Cite

Purpose Reconstruction of the canine mandible using bone transport distraction osteogenesis has been shown to be a suitable method for correcting segmental bone defects produced by cancer, gunshots, and trauma. Although the mechanical quality of the new regenerate cortical bone seems to be related to the mineralization process, several questions regarding the micro-structural patterns of the new bony tissue remain unanswered. The purpose of this study was to quantify any microstructural differences that may exist between the regenerate and control cortical bone. Methods Five adult American foxhound dogs underwent unilateral bone transport distraction of the mandible to repair 30–35 mm bone defects. Animals were sacrificed 12 weeks after the beginning of the consolidation period. Fourteen cylindrical cortical samples were extracted from the superior, medial, and inferior aspects of the lingual and buccal plates of the reconstructed aspect of the mandible and 21 specimens were collected similarly from the contralateral aspect of the mandible. The specimens were evaluated using histomorphometric and micro-computed tomography techniques to compare their microstructure. Results Except for differences in Haversian canal area, histomorphometric analyses suggested no statistical differences in microstructure between regenerate and control cortical bone. Morphological evaluation suggested a consistent level of anisotropy possibly related to the distraction vector. Conclusions After 12 weeks consolidation, bone created during bone transport distraction osteogenesis is comparable to native bone in microstructure, architecture, and mechanical properties. It is proposed that after enough time, the properties of the regenerate bone will be identical to that of native bone.

show abstract

Biomechanical characteristics of regenerated cortical bone in the canine mandible

Cited by 5 publications

References 40 publications

Biomechanics of the Canine Mandible During Bone Transport Distraction Osteogenesis

Biomechanics of the Canine Mandible During Bone Transport Distraction Osteogenesis

Can cone beam CT predict the hardness of interradicular cortical bone?

Architecture and Microstructure of Cortical Bone in Reconstructed Canine Mandibles After Bone Transport Distraction Osteogenesis

Contact Info

Product

Resources

About