To successfully conduct quality research, professionals in adapted physical activity (APA) must address a number of unique and challenging issues. These issues include difficulty in acquiring large and homogenous samples; developing valid, reliable, and commercially available test instruments and protocols specific to persons with disabilities; properly training doctoral students to conduct quality research; and maintaining a specific research focus. With regard to these issues, this paper provides the following recommendations: utilize alternative research designs; acquire adequate graduate research training; develop a research focus as an adapted physical activity researcher; and promote an interdisciplinary, collaborative research effort among professionals. Most important, through continued scholarly research adapted physical activity professionals will be able to expand the scientific body of knowledge.