Biomaterials of Poly(vinyl alcohol) and Natural Polymers

Teodorescu, Mirela; Bercea, Maria; Morariu, Simona

doi:10.1080/15583724.2017.1403928

Cited by 164 publications

(87 citation statements)

References 204 publications

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“…These values are lower for the PVA/CAR hydrogels, compared to the PVA and K hydrogels. Remarkable stability has been registered for the K/PVA 1:6 hydrogel, similar to other blends of poly (vinyl alcohol) (e.g., PVA/β-cyclodextrin gels [58], PVA-dextran gels [59] or PVA-starch films [60]).…”

Section: Shifting Of The~20supporting

confidence: 63%

Physically Crosslinked Poly (Vinyl Alcohol)/Kappa-Carrageenan Hydrogels: Structure and Applications

et al. 2020

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This paper discusses the structure morphology and the thermal and swelling behavior of physically crosslinked hydrogels, obtained from applying four successive freezing–thawing cycles to poly (vinyl alcohol) blended with various amounts of κ-carrageenan. The addition of carrageenan in a weight ratio of 0.5 determines a twofold increase in the swelling degree and the early diffusion coefficients of the hydrogels when immersed in distilled water, due to a decrease in the crystallinity of the polymer matrix. The diffusion of water into the polymer matrix could be considered as a relaxation-controlled transport (anomalous diffusion). The presence of the sulfate groups determines an increased affinity of the hydrogels towards crystal violet cationic dye. A maximum physisorption capacity of up to 121.4 mg/g for this dye was attained at equilibrium.

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Section: Shifting Of The~20supporting

confidence: 63%

Physically Crosslinked Poly (Vinyl Alcohol)/Kappa-Carrageenan Hydrogels: Structure and Applications

et al. 2020

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“…Owing to the combination of similar specific porosity and wide possibility to adjust the physico-chemical characteristics of the various cryogenically structured matrices to the requirements of the goal application, polymeric cryogels and cryostructurates have been extensively examined and used in many practical areas. The following overview publications describe and discuss the generalized data related to the applied potential of similar polymeric materials in such fields as biomaterials (the highest quantity of the respective publications) [ 5 , 12 , 13 , 16 , 17 , 38 , 45 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 ], biotechnology [ 5 , 12 , 13 , 16 , 17 , 18 , 19 , 30 , …”

Section: Introductionmentioning

confidence: 99%

Cryostructuring of Polymeric Systems. 55. Retrospective View on the More than 40 Years of Studies Performed in the A.N.Nesmeyanov Institute of Organoelement Compounds with Respect of the Cryostructuring Processes in Polymeric Systems

Lozinsky

2020

Gels

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The processes of cryostructuring in polymeric systems, the techniques of the preparation of diverse cryogels and cryostructurates, the physico-chemical mechanisms of their formation, and the applied potential of these advanced polymer materials are all of high scientific and practical interest in many countries. This review article describes and discusses the results of more than 40 years of studies in this field performed by the researchers from the A.N.Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences—one of the key centers, where such investigations are carried out. The review includes brief historical information, the description of the main effects and trends characteristic of the cryostructuring processes, the data on the morphological specifics inherent in the polymeric cryogels and cryostructurates, and examples of their implementation for solving certain applied tasks.

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“…In this context, alginate (Figure b), a natural polymer primarily isolated from brown seaweed and endowed with inimitable features such as biocompatibility, pH‐sensitivity, relative ease of fabrication of formulations and high biodegradability finds extensive applications in biomedicine . On the other hand, polyvinyl alcohol (PVA) (Figure c) is a synthetic polymer that has been widely employed in biomedical applications . Integration of PVA and alginate have resulted in the design of smart hydrogel systems for a broad spectrum of applications ranging from agriculture to dye removal, pervaporation, wound dressings, tissue engineering and drug delivery …”

Section: Introductionmentioning

confidence: 99%

Controlled Release of 5‐Fluorouracil from Alginate Hydrogels by Cold HMDSO−Plasma Surface Engineering

et al. 2020

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For decades, 5‐fluorouracil (5FU) has been the only chemotherapeutic agent to demonstrate a strong activity against colorectal cancer. However intravenous administration of 5FU mandates the development of an oral controlled delivery system for improved patient compliances. With this rationale, hydrogels comprising polyvinyl alcohol and sodium alginate were crafted and subjected to cold atmospheric plasma treatment by coating with hexamethyldisiloxane (HMDSO) using three different carrier gases viz Ar, He and N2. Surface hydrophobicity ensuing from HMDSO plasma was evident from contact angle goniometry. FT‐IR analyses were affirmative of the effectual deposition of Si−O−Si and Si−CH3 groups on the hydrogel surfaces. Moreover, plasma treatment rendered the hydrogels stiffer and tougher. The plasma‐modified hydrogels displayed lower water uptake capacity in comparison to the pristine one. Drug release was significantly prolonged from the plasma‐treated hydrogels that conformed to the oral delivery of 5FU to colon. Preliminary kinetics assay revealed drug release was predominantly governed by polymer chain relaxation process post‐plasma modification. The Ar/HMDSO‐plasma modified hydrogel was found to be best of the lot for achieving an oral controlled release for 5FU.

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Biomaterials of Poly(vinyl alcohol) and Natural Polymers

Cited by 164 publications

References 204 publications

Physically Crosslinked Poly (Vinyl Alcohol)/Kappa-Carrageenan Hydrogels: Structure and Applications

Physically Crosslinked Poly (Vinyl Alcohol)/Kappa-Carrageenan Hydrogels: Structure and Applications

Cryostructuring of Polymeric Systems. 55. Retrospective View on the More than 40 Years of Studies Performed in the A.N.Nesmeyanov Institute of Organoelement Compounds with Respect of the Cryostructuring Processes in Polymeric Systems

Controlled Release of 5‐Fluorouracil from Alginate Hydrogels by Cold HMDSO−Plasma Surface Engineering

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