Biomaterials in Guided Bone and Tissue Regenerations: An Update

Abstract

Purpose. Guided tissue reconstruction can be performed to restore the supporting structure of a previously lost tooth, which, in addition to maintaining beauty, preserves the function of the tooth in the patient. Materials and Methods. In this review, Scopus, PubMed, and MEDLINE databases were searched using the keywords “biocompatible materials,” “membrane,” “bone regeneration,” “tissue reconstruction,” and “dental biomaterials.” Overall, 150 articles were reviewed, and finally, 107 articles published during 2000–2021 were included in the final paper. Results. Studies have been conducted on a variety of membranes in both clinical and experimental settings. The first half of this article explores the different kinds of membranes and diverse classes of biomaterials used in these procedures. Secondly, biomaterials are examined for their therapeutic uses such as growth factors, stem cells, and gene delivery vehicles. Conclusion. If a tooth has been extracted or if the gums have been infected with periodontal disease, guided bone regeneration procedures may be used to restore the lost bone. Recent years have seen a variety of approaches to regenerating these tissues. To prevent nonossifying cells from entering, membranes are heavily employed during guided rebuilding.

The effect of photodynamic therapy in controlling the oral biofilm: A comprehensive overview

“…A shift toward novel implant technologies has been caused by these disadvantages. High-strength zirconia ceramic is becoming an increasingly popular material for dental implants [96,97]. Their strength and tooth-like color are both excellent, but they are also more fracture-tough than other ceramics.…”

Smart stimuli-responsive strategies for titanium implant functionalization in bone regeneration and therapeutics

“…Therefore, biomaterial-based bone regeneration has been revolving dramatically in the past several decades, which developed various material systems for different clinical scenarios. [3][4][5] For over half a century, titanium and its alloys have been used as the mainstream implant materials, attributed to its appropriate mechanical properties, high corrosion resistance, and favorable biocompatibility (Table 1). They can serve as prosthesis for total joint replacements, temporary internal fixation devices for bone fractures, or implants to restore segmental load-bearing bone defects and lost teeth.…”

“…Therefore, biomaterial-based bone regeneration has been revolving dramatically in the past several decades, which developed various material systems for different clinical scenarios. 3–5…”

Effect of Dehydrothermal Treatment on the Structure and Properties of a Collagen-Based Heterogeneous Bilayer Membrane

“…And thereinto, the barrier membranes play the most important role in the surgical method. , The epithelial cells and fibroblasts grow so fast that their migration into the space caused by bone defects could affect the alveolar bone regeneration. Consequently, the barrier membrane is placed to prevent their migration, so as to ensure sufficient space for new bone formation. , As an ideal biomedical material for bone defect, the barrier membrane should have good biocompatibility and could remain its function stable over a specified time. , Besides, the membrane should prevent the invasion of fibrous tissue and preserve the freshly generated bone tissue to maintain spatial and biomechanical stability of the defect site …”