Biomaterials for Hard Tissue Engineering: Concepts, Methods, and Applications

Saraswathy, Manju; Krishnaswami, Venkateshwaran; Ragini, Deepu Damodharan

doi:10.1007/978-981-16-0002-9_10

Cited by 1 publication

(1 citation statement)

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“…Over the last two decades, the interest in tissue engineering for the regeneration of soft and hard tissues is increasing significantly because of the growing demand for successful tissue repair. As a result, the global tissue engineering market is projected to grow to USD 28.9 billion by 2027, expanding at a CAGR of 14.2% every year from 2020 to 2027 [ 2 ]. Since biomaterials are central in regenerative tissue engineering, the demand for biomaterials has also increased significantly in recent years.…”

Section: Introductionmentioning

confidence: 99%

Bacterial Cellulose-Based Blends and Composites: Versatile Biomaterials for Tissue Engineering Applications

Raut

Asare

Mohamed

et al. 2023

IJMS

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Cellulose of bacterial origin, known as bacterial cellulose (BC), is one of the most versatile biomaterials that has a huge potential in tissue engineering due to its favourable mechanical properties, high hydrophilicity, crystallinity, and purity. Additional properties such as porous nano-fibrillar 3D structure and a high degree of polymerisation of BC mimic the properties of the native extracellular matrix (ECM), making it an excellent material for the fabrication of composite scaffolds suitable for cell growth and tissue development. Recently, the fabrication of BC-based scaffolds, including composites and blends with nanomaterials, and other biocompatible polymers has received particular attention owing to their desirable properties for tissue engineering. These have proven to be promising advanced materials in hard and soft tissue engineering. This review presents the latest state-of-the-art modified/functionalised BC-based composites and blends as advanced materials in tissue engineering. Their applicability as an ideal biomaterial in targeted tissue repair including bone, cartilage, vascular, skin, nerve, and cardiac tissue has been discussed. Additionally, this review briefly summarises the latest updates on the production strategies and characterisation of BC and its composites and blends. Finally, the challenges in the future development and the direction of future research are also discussed.

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Section: Introductionmentioning

confidence: 99%