Biomaterials derived from hard palate mucosa for tissue engineering and regenerative medicine

Ren, Lingfei; Jiang, Zhiwei; Zhang, Hui; Chen, Yani; Zhu, Danji; Jin, He; Chen, Y.; Wang, Ying; Yang, Guoli

doi:10.1016/j.mtbio.2023.100734

Cited by 1 publication

(1 citation statement)

References 110 publications

(228 reference statements)

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“…Tissue engineering is a multidisciplinary area utilizing the concepts of biology, medicine and engineering to repair, restore or regenerate damaged organs and tissues. It relies on the isolation and culture of stromal cells, proper scaffolds and an ideal extracellular matrix [75][76][77][78][79][80][81]. In the extremely difficult area of lung and airway regeneration, several cases of bioengineered tracheas have been reported in the past [82,83], albeit with very disappointing results [84,85], and the attractive idea of bioengineered tracheal substitution has not reached a definitive and reliable solution.…”

Section: Tissue Engineeringmentioning

confidence: 99%

Mesenchymal Stromal Cell Therapy for Thoracic Surgeons: An Update

Petrella,

Cassina,

Libretti

et al. 2023

JPM

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Stem cells are undifferentiated cells presenting extensive self-renewal features and the ability to differentiate “in vitro” and “in vivo” into a range of lineage cells, like chondrogenic, osteogenic and adipogenic lineages when cultured in specific inducing media. Two major domains of clinical applications of stem cells in thoracic surgery have been investigated: regenerative medicine, which is a section of translational research in tissue engineering focusing on the replacement, renewal or regeneration of cells, tissues and organs to re-establish damaged physiologic functions; drug loading and delivery, representing a new branch proposing stem cells as carriers to provide selected districts with anti-cancer agents for targeted treatments.

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