Biomass-codoped carbon dots: efficient fluorescent probes for isocarbophos ultrasensitive detection and for living cells dual-color imaging

Hu, Yuefang; Chen, Zhenming; Lai, Feiyan; Li, Jinfang

doi:10.1007/s10853-019-03494-9

Cited by 25 publications

(8 citation statements)

References 51 publications

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“…Hu et al prepared double-emitted biomass nitrogen co-doped CDs (B-NCdots) for Cu 2+ probing in T24 cells. Similarly, the quenching effect was still available for Cu 2+ , causing a decreased intensity of blue and green, as shown in Figure 6e,f [117]. Furthermore, bio-related molecules, including peptides and drug-containing cells, are even more crucial.…”

Section: Sensorsmentioning

confidence: 86%

Natural Carbon Nanodots: Toxicity Assessment and Theranostic Biological Application

et al. 2021

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This review outlines the methods for preparing carbon dots (CDs) from various natural resources to select the process to produce CDs with the best biological application efficacy. The oxidative activity of CDs mainly involves photo-induced cell damage and the destruction of biofilm matrices through the production of reactive oxygen species (ROS), thereby causing cell auto-apoptosis. Recent research has found that CDs derived from organic carbon sources can treat cancer cells as effectively as conventional drugs without causing damage to normal cells. CDs obtained by heating a natural carbon source inherit properties similar to the carbon source from which they are derived. Importantly, these characteristics can be exploited to perform non-invasive targeted therapy on human cancers, avoiding the harm caused to the human body by conventional treatments. CDs are attractive for large-scale clinical applications. Water, herbs, plants, and probiotics are ideal carbon-containing sources that can be used to synthesize therapeutic and diagnostic CDs that have become the focus of attention due to their excellent light stability, fluorescence, good biocompatibility, and low toxicity. They can be applied as biosensors, bioimaging, diagnosis, and treatment applications. These advantages make CDs attractive for large-scale clinical application, providing new technologies and methods for disease occurrence, diagnosis, and treatment research.

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Section: Sensorsmentioning

confidence: 86%

Natural Carbon Nanodots: Toxicity Assessment and Theranostic Biological Application

et al. 2021

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“…To date, amounts of research demonstrated that CDs are highly biocompatible. Hu et al [ 93 ] established the investigation of cytotoxicity of biomass nitrogen-co-doped carbon dots (B-NCdots) prepared from the pyrolysis of natural soybean as the starting material. An MTT test was employed in human bladder carcinoma cell line (T24 cells), which indicated that the B-NCdot was low in toxicity.…”

Section: Microstructure Properties Synthetic Methods and Biocompatibilitymentioning

confidence: 99%

A Critical Review of Carbon Quantum Dots: From Synthesis toward Applications in Electrochemical Biosensors for the Determination of a Depression-Related Neurotransmitter

Tao

et al. 2021

Materials

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Depression has become the leading cause of disability worldwide and is a global health burden. Quantitative assessment of depression-related neurotransmitter concentrations in human fluids is highly desirable for diagnosis, monitoring disease, and therapeutic interventions of depression. In this review, we focused on the latest strategies of CD-based electrochemical biosensors for detecting a depression-related neurotransmitter. We began this review with an overview of the microstructure, optical properties and cytotoxicity of CDs. Next, we introduced the development of synthetic methods of CDs, including the “Top-down” route and “Bottom-up” route. Finally, we highlighted detecting an application of CD-based electrochemical sensors in a depression-related neurotransmitter. Moreover, challenges and future perspectives on the recent progress of CD-based electrochemical sensors in depression-related neurotransmitter detection were discussed.

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“…All those results indicate that the CQDs are suitable materials for bioimaging. As reported [5,23], the CQDs can be used for biological application such as bioimaging, cancer diagnostic probe, gene technology, among those application, the inherent toxicity of the materials must be within limits, therefore, the cytotoxicity of CQDs was evaluated by carrying out a series of MTT assays using the Hela cells. As observed in Fig.…”

Section: Methodsmentioning

confidence: 99%

“…Carbon quantum dots (CQDs), tiny fluorescent particles, have drawn great attention as novel materials due to their excellent characteristics, such as unique luminescence, photostability, low toxicity, chemical resistance and electronic transport properties [3, 4]. In addition, CQDs can be prepared easily from a wide range of raw materials and they are particularly attractive due to their excellent bioimaging [5]. Therefore, CQDs have been proposed as promising substitutes for traditional QDs.…”

Section: Introductionmentioning

confidence: 99%

Rapid hydrothermal method for the preparation of carbon quantum dots in the presence of hydrogen peroxide

Qin¹,

Li²,

Yuan³

et al. 2020

Micro & Nano Letters

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Carbon quantum dots (CQDs) have been studied for years as one of the most promising fluorescent nanomaterials. Herein, CQDs were prepared rapidly by a simple, eco-friendly one-pot hydrothermal method in the presence of hydrogen peroxide. Different sizes of CQDs are obtained by changing the reaction time. X-ray photoelectron spectroscopy and Fourier transform infrared spectrometry demonstrated the existence of a large number of oxygen-containing groups on the surface of CQDs. The as-prepared CQDs exhibited bright yellow luminescence under UV light, they are applied for bioimaging of HeLa cells, and showed bright luminescence and excellent biocompatibility.

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Biomass-codoped carbon dots: efficient fluorescent probes for isocarbophos ultrasensitive detection and for living cells dual-color imaging

Cited by 25 publications

References 51 publications

Natural Carbon Nanodots: Toxicity Assessment and Theranostic Biological Application

Natural Carbon Nanodots: Toxicity Assessment and Theranostic Biological Application

A Critical Review of Carbon Quantum Dots: From Synthesis toward Applications in Electrochemical Biosensors for the Determination of a Depression-Related Neurotransmitter

Rapid hydrothermal method for the preparation of carbon quantum dots in the presence of hydrogen peroxide

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