Biomarkers and the prediction of adverse outcomes in patients with acute decompensated heart failure and kidney injury

Highlights. The article is a review of current literary data on the problem of acute decompensated heart failure. The review highlights the basic principles of the diagnosis and treatment, as well as the problems of their implementation into clinical practice.Abstract Acute decompensated heart failure (ADHF) is a life-threatening condition that requires an emergency hospitalization for intensive treatment. Moreover, it is the event that worsens the patient's further prognosis. Frequent rehospitalizations for decompensation of heart failure reduce life expectancy and quality, and are also a significant economic problem in practical health care. The increasing number of patients with heart failure leads to the growing number of patients seeking medical help for acute decompensated heart failure. More than half of the patients are re-hospitalized within a year for the same reason. The predicted increase in the prevalence of CHF worldwide makes the management of such patients a global medical and social problem. Patients delay, low compliance and insufficient ambulatory monitoring are the factors that need to be influenced in order to improve the prognosis. The article is a review of literary data on the epidemiology of ADHF, diagnosis, treatment and outpatient observation of patients with acute decompensated heart failure. The problems of compliance, the prospects for modern methods of remote monitoring and the possibilities of new drugs are discussed in the article.

show abstract

Chronic and acute decompensated heart failure: topical issues

Okunev¹,

Кочергина

Кашталап

2022

Kompleks. probl. serdečno-sosud. zabol.

View full text Add to dashboard Cite

show abstract

Early diagnosis of acute kidney dysfunction in combined mechanical injury (literature review)

Ivanov,

Gaiduk,

Pershko

et al. 2024

Vrach

View full text Add to dashboard Cite

The improvement of clinical and laboratory research methods contributes to the timely diagnosis and improvement of the effectiveness of disease therapy, which ensures the preservation of public health, reducing the time of temporary disability and rehabilitation of patients. The evidence base for determining the predictive role of biomarkers of renal dysfunction is small and is available only for a very limited number of substances – some serum proteins, the synthesis of which increases with acute kidney injury, low molecular weight urine proteins, intracellular enzymes of tubular epithelial cells and some other substances. This article provides an overview of modern laboratory methods of early diagnosis of kidney dysfunction in combined mechanical injury.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Biomarkers and the prediction of adverse outcomes in patients with acute decompensated heart failure and kidney injury

Cited by 2 publications

References 22 publications

Chronic and acute decompensated heart failure: topical issues

Chronic and acute decompensated heart failure: topical issues

Early diagnosis of acute kidney dysfunction in combined mechanical injury (literature review)

Contact Info

Product

Resources

About