Biomarker Identification for Preterm Birth Susceptibility: Vaginal Microbiome Meta‐Analysis Using Systems Biology and Machine Learning Approaches
Sudeepti Kulshrestha,
Priyanka Narad,
Brojen Singh
et al.
Abstract:ProblemThe vaginal microbiome has a substantial role in the occurrence of preterm birth (PTB), which contributes substantially to neonatal mortality worldwide. However, current bioinformatics approaches mostly concentrate on the taxonomic classification and functional profiling of the microbiome, limiting their abilities to elucidate the complex factors that contribute to PTB.Method of studyA total of 3757 vaginal microbiome 16S rRNA samples were obtained from five publicly available datasets. The samples were… Show more
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