Biology and Diseases of Swine

Helke, Kristi L.; Ezell, Paula C.; Duran‐Struuck, Raimon; Swindle, M. Michael

doi:10.1016/b978-0-12-409527-4.00016-x

Cited by 27 publications

(16 citation statements)

References 357 publications

(314 reference statements)

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“…Morphometrical and biochemical approaches are the most used techniques to evaluate small intestine structure and function, as they provide reliable results 12 , 13 . For example, intestinal maturity is extensively assessed by studying the size and number of villi, mucosal height, crypts depth, and enterocyte height 4 , 14 , 15 .…”

Section: Introductionmentioning

confidence: 99%

Intrauterine growth restriction and its impact on intestinal morphophysiology throughout postnatal development in pigs

Santos

Fernandes

Araújo

et al. 2022

Sci Rep

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Intrauterine growth restriction (IUGR) compromises fetal development, leading to low birth weight, and predisposes to gastrointestinal disorders. Pigs that suffered IUGR present poor postnatal development, resulting in great economic losses to the industry. The small intestine may be involved with impaired development, but studies investigating this issue are still limited. Thus, the present study aimed to investigate small intestine morphofunctional alterations in IUGR pigs throughout the production phases (birth to 150 days). IUGR pigs presented lower body weight from birth to the finishing phase (P < 0.05). Although histomorphometrical parameters were not affected during the pre-weaning period, their commitment was observed specifically in the duodenum of the IUGR group at older ages (P < 0.05). The most detrimental effects on the small intestine, such as deeper duodenum crypts’ depth, lower villus height:crypt depth ratio and absorptive area, increased apoptosis and lower proliferation of the duodenum epithelium were noticed at 70 days of age (P < 0.05). Additionally, IUGR pigs presented the lowest chymotrypsin and amylase activities at 70 and 150 days of age, respectively (P < 0.05). These findings may contribute to the elucidation of morphofunctional disorders of the small intestine in IUGR pigs throughout the different production phases, suggesting that poor postnatal development may be due to intestinal damage.

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Section: Introductionmentioning

confidence: 99%

Intrauterine growth restriction and its impact on intestinal morphophysiology throughout postnatal development in pigs

Santos

Fernandes

Araújo

et al. 2022

Sci Rep

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show abstract

“…Among thirty-nine isolates of S. suis obtained from clinical samples of diseased pigs from fifteen pig farms located in the Czech Republic (CZ) and one farm in Slovakia, a number of different serotypes and STs were found. Seven isolates were not typable by the multiplex PCR used [ 27 ] and also STs of unknown type was found in thirteen isolates. Curiously, none of the three isolates of serotype 16 had known ST.…”

Section: Discussionmentioning

confidence: 99%

“…Management techniques that integrate technology into disease control, elimination and eradication have been further levelled up by repopulating the entire herd by eliminating serious infections caused by A. pleuropneumoniae , etc., to avoid further medication and cost increases [ 27 ]. A more detailed analysis of S. suis characteristics in repopulated specific pathogen free (SPF) herds in Central Europe has not yet been carried out.…”

Section: Introductionmentioning

confidence: 99%

Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms

et al. 2021

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Streptococcus suis represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decades to reduce morbidity and minimize treatment. The study analysed serotypes, sequence types and antimicrobial susceptibility in 39 S. suis isolates obtained from organs of diseased pigs from selected 16 repopulated farms with a history of S. suis-associated diseases and routine antimicrobial treatment with tulathromycin and/or amoxicillin. The analysis revealed diversity of collected isolates with regular occurrence of more than three serotypes per farm. The serotypes identified were 1/2 and 7, each in six isolates, followed by serotype 2 and 3 found in five isolates each, other serotypes were less frequent. Seven isolates were not typable by multiplex PCR and we also found sequence type of unknown type in thirteen isolates. The majority of S. suis isolates were resistant to clindamycin (n = 31), tetracycline (n = 29) and tilmicosin and tulathromycin (n = 28). On the other hand, with the exception of two isolates that were intermediately susceptible to penicillin and ampicillin, all isolates were susceptible to all three tested subgroups of beta-lactam antibiotics.

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“…Morphometrical and biochemical approaches are the most used techniques in animal science to evaluate small intestine structure and function, as they provide reliable results [12,13]. For example, intestinal maturity is extensively assessed by studying the size and number of villi, mucosal height, crypts depth, and epithelium height [4,14,15].…”

Section: Introductionmentioning

confidence: 99%

Intrauterine Growth Restriction and Its Impact on Intestinal Morphophysiology Throughout Postnatal Development in Pigs

Santos

Fernandes

Araújo

et al. 2022

Preprint

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Intrauterine growth restriction (IUGR) compromises fetal development, leading to low birth weight, and predisposes to gastrointestinal disorders. Pigs that suffered IUGR present poor postnatal development, resulting in great economic losses to the industry. The small intestine may be involved with their growth commitment, but studies investigating this issue are still limited. Thus, the present study aimed to investigate small intestine morphofunctional alterations in IUGR pigs throughout the production phases (birth to 150 days). IUGR pigs presented lower body weight from birth to the finishing phase (P<0.05). Although histomorphometrical parameters were not affected during the pre-weaning period, their commitment was observed specifically in the duodenum of the IUGR group at older ages (P<0.05). The most detrimental effects on the small intestine, such as highest duodenum crypts’ depth, lowest villus height:crypt depth ratio and absorptive area, increased apoptosis and lower proliferation of the duodenum epithelium were noticed at 70 days of age (P<0.05). Additionally, IUGR pigs presented the lowest chymotrypsin and amylase activities at 70 and 150 days of age, respectively (P<0.05). These findings showed intestinal disturbances in IUGR pigs throughout the different production phases, demonstrating that poor performance is a consequence of intestinal damage mainly at the grower period.

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Biology and Diseases of Swine

Cited by 27 publications

References 357 publications

Intrauterine growth restriction and its impact on intestinal morphophysiology throughout postnatal development in pigs

Intrauterine growth restriction and its impact on intestinal morphophysiology throughout postnatal development in pigs

Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms

Intrauterine Growth Restriction and Its Impact on Intestinal Morphophysiology Throughout Postnatal Development in Pigs

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