Biologics and Non-Biologics Immunosuppressive Treatments for IgA Nephropathy in Both Adults and Children
Decimo Silvio Chiarenza,
Enrico Eugenio Verrina,
Edoardo La Porta
et al.
Abstract:Immunoglobulin A nephropathy represents the most prevalent cause of glomerulonephritis worldwide and may lead to renal failure in a relevant number of cases in both paediatric and adult subjects. Although their pathogenesis is still largely unclear, evidence of immune abnormalities provides the background for the use of immunosuppressive drugs, such as corticosteroids, calcineurin inhibitors, and antiproliferative and alkylating agents. Unfortunately, these treatments fail to achieve a sustained remission in a… Show more
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