Biologically Active Substances of Cephalaria Gigantea Growing in Georgia

Tabatadze, Nino; Tsomaia, Irma; Chikovani, Anton; Gigoshvili, T. I.

doi:10.29013/ajt-20-5.6-22-25

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…This compound was also isolated from the C. scoparia acetone extract (3.1 mg) [ 58 ]. From the aerial parts of C. elmaliensis cynaroside ( 14 , 2.4 mg) [ 58 ] and tiliroside (kaempferol 3- O -β-D-(6″- O -( E )- p -coumaroyl)glucopyranoside, 4 ) were isolated [ 57 ]. Quercitrin was identified in the ethyl acetate and aqueous fractions from the roots of C. gigantea [ 42 , 59 ].…”

Section: Phenolic Compounds In the Cephalaria Speciesmentioning

confidence: 99%

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Chrząszcz

Krzemińska

Skowronek

et al. 2021

Plants

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The genus Cephalaria, belonging to the Caprifoliaceae family, is a rich source of interesting secondary metabolites, including mainly saponins which display a variety of biological activities, such as immunomodulatory, antimicrobial and hemolytic effects. Besides these compounds, flavonoids and phenolic acids were identified in Cephalaria species. Cephalaria is employed in traditional medicine e.g., to cure cardiac and lung diseases, rheumatism, and regulate menstruation. In this review we focus on the phenolic compound composition and antioxidative activity of Cephalaria species. The antioxidant effect can be explained by flavonoids present in all parts of these plants. However, future efforts should concentrate more on in vitro and in vivo studies and also on clinical trials in order to confirm the possibility of using these plants as natural antioxidants for the pharmacology, food or cosmetic industries.

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Section: Phenolic Compounds In the Cephalaria Speciesmentioning

confidence: 99%

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Chrząszcz

Krzemińska

Skowronek

et al. 2021

Plants

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show abstract

“…Due to the presence of a variety of chemical constituents, these plants are attractive species from a medicinal perspective. Investigated Cephalaria species have been shown to exhibit broad cytotoxic activity [16], e.g., antifungal [18], antiprotozoal [19], and antibacterial [20] effects. They are also rich in many secondary metabolites with antioxidant properties [21].…”

Section: Introductionmentioning

confidence: 99%

Biotechnological Potential of Cephalaria uralensis (Murray) Roem. & Schult. and C. gigantea (Ledeb.) Bobrov—Comparative Analysis of Plant Anatomy and the Content of Biologically Active Substances

Chrząszcz

Szewczyk

Tchórzewska

2021

Plants

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Studies conducted to date have shown that Cephalaria uralensis and C. gigantea have high contents of substances with antibacterial, anti-inflammatory, and antioxidant properties; hence, they are attractive plants from the pharmaceutical point of view. However, despite their multifarious desirable biotechnological aspects, the knowledge of these plants is insufficient. The present study focused on the analysis of the morphological, anatomical, and histological structure of aboveground parts of the plants, the identification of the distribution of biologically active compounds in the tissues, and quantitative phytochemical analyses of polyphenolic compounds contained in their aboveground organs. Importantly, the phenological and morphological features of the aboveground organs in the analyzed species were maintained, as in the same plant species growing in different climatic conditions. The analysis of primary metabolites and phenolic compounds in the tissues revealed their distribution in the aboveground organs, which has never been described before. The comparative analyses of the content of total phenolics, total phenolic acids, and total flavonoids in the aboveground organs showed that the level of these substances differed not only between the species but also between the organs. It should be emphasized that the level of these compounds is higher than in many other medicinal plants.

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Biologically Active Substances of Cephalaria Gigantea Growing in Georgia

Cited by 2 publications

References 8 publications

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Biotechnological Potential of Cephalaria uralensis (Murray) Roem. & Schult. and C. gigantea (Ledeb.) Bobrov—Comparative Analysis of Plant Anatomy and the Content of Biologically Active Substances

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